Results 31 to 40 of about 331,055 (264)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Drikkeskikker og politisk kultur i Telemark på 1800-tallet

open access: yesHeimen, 2019
In Norway in the 19th and 20th century the consumption of liquor formed the basis for a peculiar political culture manifested in restrictive alcohol legislation in combination with a strong temperance movement.
Ellen Schrumpf
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

«Underretning fra fjeldet»Språkspørsmålet i avisa Waren Sardne og andre deler av den sørsamiske offentligheten de første tiåra av 1900-tallet

open access: yesHeimen
I artikkelen belyser jeg hvordan tema som skolespørsmålet, opplæring på samisk og den rådende fornorskingspolitikken er representert i den sørsamiske avisa Waren Sardne (1910–1913, 1922–1927) og den såkalte samespalten, «Til og fra lapperne», i ...
Asbjørn Rørslett Kolberg
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Et lokalt engasjement i en «taus» tid: Prosessen med å skape «Kvenmuseet»

open access: yesHeimen
I denne artikkelen blir konteksten rundt etableringen av et kvensk museum i Vadsø i 1971 utforsket. Utgangspunktet for museumsdannelsen var overtakelsen av en kvensk eiendom (Tuomainengården), som ble testamentert til Vadsø kommune for å bli et ...
Gyrid Øyen
doaj   +1 more source

Okkupasjonens kulturminner

open access: yesHeimen, 2020
Sammendrag Denne artikkelen ser på bruken av historiske flyfoto som et redskap for å kartlegge moderne bygde miljø og andre verdenskrigs påvirkning av landskapet.
Julian P. Cadamarteri   +1 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Mellom Sundsvall og SmølaEn mikrohistorisk undersøkelse av to samiske familier på 1800-tallet

open access: yesHeimen
Med mikrohistorisk metode og transnasjonal tilnærming tar vi i artikkelen for oss historien til bofaste og delvis bofaste samer på 1800-tallet i den sørlige delen av Saepmie.
Håkon Hermanstrand, Ann-Kristin Solsten
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

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