Results 191 to 200 of about 187,427 (307)

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Widespread terrestrial ecosystem disruption at the onset of the Paleocene-Eocene Thermal Maximum. [PDF]

Proc Natl Acad Sci U S A
Nelissen M, Willard DA, van Konijnenburg-van Cittert H, Bowen GJ, Hollaar T, Sluijs A, Frieling J, Brinkhuis H.   +7 more
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Genetic Markers for Tracing Introgression of Farmed Atlantic Salmon (Salmo salar) in Wild Conspecifics. [PDF]

Mol Ecol Resour
Hagen IJ, Hindar K, Bolstad GH, Czorlich Y, Diserud OH, Florø-Larsen B, Gíslason D, Glover K, Guðmundsson LA, Jacq C, Ólafsdóttir G, Omholt SW, Solberg MF, Sveinsson S, Sægrov H, Urdal K, Karlsson S.   +16 more
europepmc   +1 more source

Site 642: Norwegian Sea

, 1987
openaire   +1 more source

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Biodiversity changes in Arctic coastal ecosystems under borealization. [PDF]

PNAS Nexus
Descamps S, Jungblut S, Yoccoz NG, Schlegel R, Kovacs KM, Merkel F, Renaud PE, Sen A, Søreide JE, Vader A, Bailey A, Berge J, Düsedau L, Gabrielsen GW, Hanssen SA, Hop H, Jørgensen LL, Lydersen C, Marnela M, Merillet L, Moe B, Sauser C, Systad GH, Wold A, Bischof K.   +24 more
europepmc   +1 more source

The Norwegian North-Sea Expedition 1 [PDF]

Nature, 1883
openaire   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Metabarcoding and targeted barcoding can enhance Norwegian Continental Shelf macrofauna species inventories. [PDF]

PeerJ
Hestetun JT, Lanzén A, Kongsrud JA, Alvestad T, Johansen PO, Dahlgren TG.   +5 more
europepmc   +1 more source