Results 61 to 70 of about 2,486,691 (303)

Evaluation of expression levels of Micro-RNA-378, Micro-RNA -103, and Micro-RNA-497 in melanoma [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز
Background. The aim of this study was to investigate the relative changes in the expression levels of these genes in melanoma tumor samples. Methods. During this study, 40 tumor samples and 40 samples of marginal tissue around the tumor were collected ...
Faria Aslani   +2 more
doaj   +1 more source

MALIGNANT DISEASE OF NOSE AND THROAT [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1899
It is well known to all of us that statistics, those figures which do occasionally lie, have shown that malignant disease is apparently increasing among mankind. I have seen no statistics to prove whether this is altogether an absolute increase or whether it is to some extent a relative one.
openaire   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

Distribution of Patients Referred From the Emergency Department to the Otolaryngology Clinic

open access: yesSouthern Clinics of Istanbul Eurasia, 2019
Objective: Emergency departments (EDs) are overcrowded with patients having ear, nose, and throat (ENT) complaints. A large proportion of patients are not true emergencies. Therefore, understanding patient demographics and referral patterns are important
Melis Demirağ Evman   +2 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

open access: yesAdvanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li   +9 more
wiley   +1 more source

Nose picking and nasal carriage of Staphylococcus aureus

open access: yes, 2006
OBJECTIVE: Nasal carriage of Staphylococcus aureus is an important risk factor for S. aureus infection and a reservoir for methicillin-resistant S. aureus. We investigated whether nose picking was among the determinants of S.
Wertheim, Heiman F.L.   +7 more
core   +1 more source

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