Results 121 to 130 of about 19,492,817 (319)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

C043 | ABSTRACT WITHDRAWN

open access: yesHaematologica
Not presented.
Data not available.
doaj  

Short Term Risk of Type 2 Diabetes in Patients Using Various Antidepressants Compared with Patients Using Fluoxetine

open access: yesPsychiatry and Clinical Psychopharmacology
Background: The objective is to compare the risk of developing type 2 diabetes (T2D) within a year in patients prescribed various antidepressants (ADs) and those prescribed fluoxetine as a control group.
Hee-Cheol Kim
doaj   +1 more source

The distribution of Transverse Aeolian Ridges on Mars [PDF]

open access: yes, 2008
not ...
Balme, M. R.   +3 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

DP075 | ABSTRACT WITHDRAWN

open access: yesHaematologica
Not presented.
Data not available.
doaj  

Icelandic debris flow and their relationship to martian gullies [PDF]

open access: yes, 2008
not ...
Balme, M. R.   +4 more
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

P069 | ABSTRACT WITHDRAWN

open access: yesHaematologica
Not presented.
Data not available.
doaj  

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