Results 61 to 70 of about 3,868,289 (277)
[Review of] David Mason, ed. Explaining Ethnic Differences: Changing Patterns of Disadvantage in Britain [PDF]
, 2005 A series of communal disturbances took place in several north of England towns during the spring and summer of 2001. They were notable for the participation of young, male Asians, a significant proportion of them Muslims...as against African ...
Miller, William L.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Un espectroscopio casero de notable performance
Revista de Enseñanza de la Física, 2016 lt is possible to built an excellent low cost spectroscope using a piece of "compact disk" as a diffraction pattern, taking advantage of the excellent regularity and thinness of its lines. We presents in this paper the constructive details, some analysis
Lorenzo Marcos Iparraguirre
doaj
Notable trends in the EU budget [PDF]
The European Union budget has a number of specific characteristics which make it different from the budgets of the Member States : in principle, it must never be in deficit, and there is a special decision-making procedure.
E. De Prest, H. Geeroms, P. Butzen
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Notorious to Notable: The Crucial Role of the Philanthropic Community in Transforming the Juvenile Justice System in Washington, D.C. [PDF]
, 2011 Describes how foundations helped transform the district's juvenile justice system, replacing a large prison with a smaller facility designed for rehabilitation and development, and reduced recidivism using community-based alternatives.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Social Media: A notable cause of child burns
Burns OpenObjective: Scalding and flame burns come first in the etiology of pediatric burns. Today, with the increase in internet use, the effect of social media on the etiology of burns is also seen.
Sabriye Dayı +5 more
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Menorah Review (No. 77, Summer/Fall, 2012) [PDF]
, 2012 A Golden Poet of Spain\u27s Golden Age -- Beyond the Second Coming -- Books in Brief: New and Notable -- Cantorial Challenges -- Jewishness in the World: A Chabad Definition -- Moreshet - From the Classics: A 1797 Wedding -- Painful Presence: Jews in ...
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