Results 271 to 280 of about 566,967 (348)

A Morphological Study of Suprascapular Notch in Population of Bihar

, 2017
Nafees Fatima, Shamir Rahman, Bipin Kumar   +2 more
openalex   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Split Ends Inhibits the Dedifferentiation of imINP to Prevent the Generation of Supernumerary Type II Neuroblasts in <i>Drosophila</i>. [PDF]

Cells
Zhou Q, Zhang F, Gong S, Zhang S, Gong W, Rui M, Wang S.   +6 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling

Disease Models & Mechanisms
Lorraine Eley, Rachel V. Richardson, Ahlam Alqahtani, Bill Chaudhry, Deborah J. Henderson   +4 more
doaj   +1 more source

Targeting asymmetric division in cancer stem cells: implications for relapse and resistance. [PDF]

Cancer Cell Int
Latifi M, Sani M, Sani F.
europepmc   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Chronic stress drives ovarian cancer progression via myeloid-derived suppressor cells infiltration and Notch signaling pathway activation. [PDF]

Front Immunol
Rivera-López YA, Torres-Rosado AP, Casiano-Martínez JA, Meléndez-Rodríguez LL, Imad-Hamad R, Hernández-Carrasquillo SM, Rivera-Pérez LM, Ortiz-León M, Torres-Rodríguez OI, Aquino-Acevedo AN, Castillo-Ocampo Y, Duffey G, Pérez-Morales J, Townsend MK, Peres LC, Rodriguez PC, Tworoger SS, Armaiz-Pena GN.   +17 more
europepmc   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

HIF1α Attenuated the Lung Ischemia-Reperfusion Injury by Activating the miR-485/Notch1 Signalling. [PDF]

J Cell Mol Med
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J.   +6 more
europepmc   +1 more source