Results 11 to 20 of about 26,639 (292)
SSRN Electronic Journal, 2015 We develop a conceptual framework which captures the e¤ect of the VAT system on profit by two effective taxes. This allows (i) predictions of the determinants of voluntary registration and bunching at the registration threshold; (ii) develops a formula for estimating the elasticity of value-added with respect to the statutory tax.
Li Liu, Ben Lockwood
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Fracture mechanics approach to design analysis of notches, steps and internal cut-outs in planar components [PDF]
, 2007 A new approach to the assessment and optimization of geometric stress-concentrating features is proposed on the basis of the correspondence between sharp crack or corner stressfield intensity factors and conventional elastic stress concentration factors (
Gray, T.G.F., Wood, J.
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Molecular and Cellular Biology, 2010 Notch receptors are transmembrane receptors that regulate cell fate decisions. There are four Notch receptors in mammals. Upon binding to members of the Delta and Jagged family of transmembrane proteins, Notch is cleaved and the Notch intracellular domain (NICD) is released.
Stefano, Zanotti, Ernesto, Canalis
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Rapid Profiling of Marine Notches Using a Handheld Laser Distance Meter [PDF]
, 2012 A rapid, single-user profiling method for rocky shores is described. The Leica Disto D8 handheld laser distance meter measures distance up to 100 m and inclination in 360 degrees.
Kázmér, Miklós, Taborosi, Danko
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Journal of Cell Biology, 2009 Cell–cell signaling mediated by the Notch receptor is iteratively involved in numerous developmental contexts, and its dysregulation has been associated with inherited genetic disorders and cancers. The core components of the signaling pathway have been identified for some time, but the study of the modulation of the pathway in different cellular ...
Tien, An-Chi +2 more
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Osteohematology: To be or Notch to be
Journal of Cellular Physiology, 2023 AbstractOsteohematology is an emerging research field that studies the crosstalk between hematopoietic and bone stromal cells, to elucidate the mechanisms of hematological and skeletal malignancies and diseases. The Notch is an evolutionary conserved developmental signaling pathway, with critical roles in embryonic development by controlling cell ...
Emel Rothzerg +4 more
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Cell Stem Cell, 2008 Notch signaling is essential for hematopoietic stem cell (HSC) formation during embryogenesis, and hitherto it was also thought to be required for HSC maintenance. However, in this issue of Cell Stem Cell, Maillard et al. (2008) demonstrate rather conclusively that inactivation of the Notch pathway in HSCs does not interfere with their self-renewal.
Gering, M, Patient, R
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Modeling of residual stresses distribution into hardened flat details with V-type notches
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2010 It is researched the residual stresses into the surface hardening details with V-type notches. It is established that depth of the notches exerts significant effect on the distribution of behavior of residual stresses distribution within notches region.
Vladimir S Vakuljuk
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Journal of Pediatric Orthopaedics B, 1997 Ultrasound images of dysplastic and/or unstable hips often display an indentation or notch at the superolateral part of the acetabulum where the iliac wing joins the acetabular roof. We reviewed the ultrasound and subsequent radiographic examinations of 295 babies examined in our hip screening clinic.
N.M. Portinaro, D. Murray, M. K. Benson
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Notch signaling and Notch signaling modifiers [PDF]
The International Journal of Biochemistry & Cell Biology, 2011 Originally discovered nearly a century ago, the Notch signaling pathway is critical for virtually all developmental programs and modulates an astounding variety of pathogenic processes. The DSL (Delta, Serrate, LAG-2 family) proteins have long been considered canonical activators of the core Notch pathway. More recently, a wide and expanding network of
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