Results 21 to 30 of about 23,253 (298)
Journal of Cell Biology, 2009 Cell–cell signaling mediated by the Notch receptor is iteratively involved in numerous developmental contexts, and its dysregulation has been associated with inherited genetic disorders and cancers. The core components of the signaling pathway have been identified for some time, but the study of the modulation of the pathway in different cellular ...
Tien, An-Chi +2 more
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Numerical simulation on the interaction of longitudinal guided waves with double defects in pipes
You-qi chuyun, 2021 In guided-wave based pipeline non-destructive inspection, it is inevitable that guided waves will interact with multiple defects, which makes damage identification more challenging.
Xiongwei HU, Xin FENG, Jing ZHOU
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Creep behavior of V-notched components [PDF]
Fracture and Structural Integrity, 2017 Geometrical discontinues such as notches play a significant rule in structural integrity of the components, especially when the component is subjected to very severe conditions, such as the high temperature fatigue or creep.
P. Gallo +4 more
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The EMBO Journal, 2015 The self‐renewal and differentiation of tissue stem cells must be tightly controlled. Unrestrained self‐renewal leads to over‐proliferation of stem cells, which may cause tumor formation, while uncontrolled differentiation leads to depletion of the stem cell pool. In this issue of The
Xiaolei, Yin, Jeffrey M, Karp
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Cell Stem Cell, 2008 Notch signaling is essential for hematopoietic stem cell (HSC) formation during embryogenesis, and hitherto it was also thought to be required for HSC maintenance. However, in this issue of Cell Stem Cell, Maillard et al. (2008) demonstrate rather conclusively that inactivation of the Notch pathway in HSCs does not interfere with their self-renewal.
Gering, M, Patient, R
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Modeling of residual stresses distribution into hardened flat details with V-type notches
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2010 It is researched the residual stresses into the surface hardening details with V-type notches. It is established that depth of the notches exerts significant effect on the distribution of behavior of residual stresses distribution within notches region.
Vladimir S Vakuljuk
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Indentation effect on the fatigue limit of axle steel
工程科学学报, 2016 A hardness tester was used to make indentations on the hourglass fatigue specimens of axle steel,and notches were machined by electronic discharge machining(EDM).The fatigue limits of both indentation specimens and notched ones were examined and compared
GAO Jie-wei +4 more
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Journal of Pediatric Orthopaedics B, 1997 Ultrasound images of dysplastic and/or unstable hips often display an indentation or notch at the superolateral part of the acetabulum where the iliac wing joins the acetabular roof. We reviewed the ultrasound and subsequent radiographic examinations of 295 babies examined in our hip screening clinic.
N.M. Portinaro, D. Murray, M. K. Benson
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Notch signaling and Notch signaling modifiers [PDF]
The International Journal of Biochemistry & Cell Biology, 2011 Originally discovered nearly a century ago, the Notch signaling pathway is critical for virtually all developmental programs and modulates an astounding variety of pathogenic processes. The DSL (Delta, Serrate, LAG-2 family) proteins have long been considered canonical activators of the core Notch pathway. More recently, a wide and expanding network of
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, 2019 This paper shows that the sufficient statistic approach to the welfare properties of income (and other) taxes does not easily extend to tax systems with notches, because with notches, changes in bunching induced by changes in tax rates have a first-order ...
Lockwood, Ben
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