Results 91 to 100 of about 4,008,312 (388)
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Revisiting Alaska's Sex Offender Registration and Public Notification Statute [PDF]
Originally published in the Alaska Justice Forum 25(1–2): 2–5 (Spring/Summer 2008)This article examines the background and judicial interpretation of Alaska's sex offender registration and public notification statute, the new federal requirements for ...
Periman, Deborah
core +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Responsabilidade dos profissionais de saúde na notificação dos casos de violência
Resumo A violência, em suas diversas formas e manifestações, não pode ser vista pelos profissionais de saúde como questão alheia a seu trabalho. Este estudo teve como objetivo analisar a responsabilidade desses profissionais na notificação dos casos de ...
Bruno Gonçalves de Oliveira+5 more
doaj +1 more source
Collection of Cryptocurrency Customer-Information: Tax Enforcement Mechanism or Invasion of Privacy? [PDF]
After granting permission to the Internal Revenue Service to serve a digital exchange company a summons for user information, the Federal District Court for the Northern District of California created some uncertainty regarding the privacy of ...
Elliott, Austin
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
A Little Common Sense is a Dangerous Thing: The Inherent Inconsistency Between KSR and Current Official Notice Policy [PDF]
[Excerpt] “The question of whether an invention is an obvious variation of existing technology is one that has troubled courts for decades. From its roots in nineteenth century case law to the recent Supreme Court decision KSR v.
Sheets, Eli M.
core +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source