Results 91 to 100 of about 4,008,312 (388)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Society Notices [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1893
n ...
openaire   +2 more sources

Revisiting Alaska's Sex Offender Registration and Public Notification Statute [PDF]

open access: yes, 2008
Originally published in the Alaska Justice Forum 25(1–2): 2–5 (Spring/Summer 2008)This article examines the background and judicial interpretation of Alaska's sex offender registration and public notification statute, the new federal requirements for ...
Periman, Deborah
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Responsabilidade dos profissionais de saúde na notificação dos casos de violência

open access: yesRevista Bioética
Resumo A violência, em suas diversas formas e manifestações, não pode ser vista pelos profissionais de saúde como questão alheia a seu trabalho. Este estudo teve como objetivo analisar a responsabilidade desses profissionais na notificação dos casos de ...
Bruno Gonçalves de Oliveira   +5 more
doaj   +1 more source

Collection of Cryptocurrency Customer-Information: Tax Enforcement Mechanism or Invasion of Privacy? [PDF]

open access: yes, 2017
After granting permission to the Internal Revenue Service to serve a digital exchange company a summons for user information, the Federal District Court for the Northern District of California created some uncertainty regarding the privacy of ...
Elliott, Austin
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

A Little Common Sense is a Dangerous Thing: The Inherent Inconsistency Between KSR and Current Official Notice Policy [PDF]

open access: yes, 2012
[Excerpt] “The question of whether an invention is an obvious variation of existing technology is one that has troubled courts for decades. From its roots in nineteenth century case law to the recent Supreme Court decision KSR v.
Sheets, Eli M.
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

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