Results 131 to 140 of about 4,008,312 (388)

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

WARN and EDWAA: Use \u27em or Lose \u27em: An Interview with Greg LeRoy, Research Director, MCLR [PDF]

open access: yes, 1992
[Editor\u27s Note] The Worker Adjustment and Retraining Notification (WARN) Act is the federal law that requires companies with 100 or more workers to provide 60 days notice of a plant closing or mass layoff. It took effect in February 1989. The Economic

core   +1 more source

A comparative study of model ingredients: fragmentation in heavy-ion collisions using quantum molecular dynamics model

open access: yes, 2010
We aim to understand the role of NN cross-sections, equation of state as well as different model ingredients such as width of Gaussian, clusterisation range and different clusterisation algorithms in multifragmentation using quantum molecular dynamics ...
A. Bonasera   +69 more
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Least Squares Regression Estimations Based on Censored Data with Measurement Errors [PDF]

open access: yes
[[notice]]補正完畢[[journaltype]]國內[[booktype]]紙本[[countrycodes ...
Huang, Wen-tao
core  

Festo: Blessing to Patent Holders or Thorn in Their Sides? [PDF]

open access: yes, 2002
The Supreme Court makes another attempt to strike a balance between protecting an inventor\u27s patent rights and ensuring adequate notice to the public of what constitutes patent infringement. This iBrief discusses the Supreme Court ruling in Festo Corp.
Miller, Jennifer
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

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