Results 211 to 220 of about 3,645,817 (330)
Retraction notice to "Applications of T-spherical fuzzy aczel-alsina power muirhead mean operators in identifying the most effective water purification process for commercial purpose" [Heliyon 10 (2024) e39524]. [PDF]
Ali R, Khan Q, Khan HU.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Retraction notice to "CRISPLD1 promotes gastric cancer progression by regulating the Ca<sup>2+</sup>/PI3K-AKT signaling pathway" [Heliyon 10 (2024) e27569]. [PDF]
Hu L +7 more
europepmc +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Retraction notice to "Beneficial effect of <i>Caesalpinia pulcherrima</i> linn., on diabetic <i>neuropathy,</i> cognitive dysfunction and cardiac complications in streptozotocin-induced diabetic rats" [Heliyon 10 (2024) e39774]. [PDF]
AnandaKumar SR +5 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

