Correction: Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy. [PDF]
PLOS One Editors.
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XLIV.—Notice of two Lumbrici with bifid hinder ends [PDF]
F. Jeffrey Bell
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
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Retraction Notice to: circRAPGEF5 Contributes to Papillary Thyroid Proliferation and Metastatis by Regulation miR-198/FGFR1. [PDF]
Liu W, Zhao J, Jin M, Zhou M.
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XXXII.—Notice of some Fungi collected by C. Darwin, Esq., during the expedition of H. M. Ship Beagle [PDF]
M. J. Berkeley
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Correction: Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro. [PDF]
PLOS ONE Staff.
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Statistical Notices of One Hundred and Twenty Cases of Carcinoma Uteri, with Remarks [PDF]
J. C. W. Lever
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