Results 161 to 170 of about 139,686 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Psychological Responses to Breast Density Notification: Empowerment or Anxiety? [PDF]

Health Expect
Mou J, Zheng S.
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Exploring Innovation in multi-agency settings for supporting children and families affected by domestic abuse: police notification schemes [PDF]

The CAFADA project (Developing the Evidence Base for Innovation in Social Care for Children and Families Impacted by Domestic Abuse) examines innovations in multi-agency responses to domestic abuse, focusing on police notification schemes designed to ...
Bellussi, Laura, Ash, Daniel P, Malloch, Margaret   +2 more
core  

Reply: Psychological Responses to Breast Density Notification: Empowerment or Anxiety? [PDF]

Health Expect
Gram EG, Houssami N, McCaffery K, Hudson C, Isautier J, Nickel B.   +5 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Alternative models of consent in out-of-hospital transfusion trials: a CAN-PATT position statement supporting exception from prospective consent with opt-out notification. [PDF]

Scand J Trauma Resusc Emerg Med
Peddle M, Greene A, Trojanowski J, Shih AW, Chang E, Nahirniak S, Pearson D, Prokopchuk-Gauk O, Martin D, Musuka C, Seidl C, Lin Y, MacDonald S, Richards L, Farrell M, Miller D, McGowan M, Nolan B.   +17 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Provincial variability in congenital heart disease prevalence in Argentina, 2014-2019: A population-based analysis from national registry data. [PDF]

PLOS Glob Public Health
Vita MC, Fantozzi N, Méndez Ortiz F, Di Lullo L, Kokal R, Peralta S, Di Lalla S.   +6 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source