Results 241 to 250 of about 139,686 (310)

Parental Notification

, 1983

core  

Patient Perspectives on Electronic Communication of Cancer Diagnoses.

JAMA Netw Open
Bhalla S, Patel MJ, Abruzzo L, Christie A, Garg R, Xie D, Louissaint J, Zhang S, Kitzman H, Gerber DE.   +9 more
europepmc   +1 more source

Sputum-negative pulmonary tuberculosis in Shanghai, China: notification, clinical characteristics and outcomes. [PDF]

BMC Infect Dis
Wu Z, Zhou Y, Chen J, Rao L, Xiao X, Zu P, Shen X, Zhang W.   +7 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Impact of Drug-Resistant Tuberculosis Prevention and Control Strategies in Southeast China: Evidence from a Longitudinal Study on Disease Epidemic Trends and Predictions Across 15 Years. [PDF]

Infect Drug Resist
Wu Y, Li M, Zhu Y, Peng Y, Wang F, Chen X, Zu Z, Chen B, Zhou L, Chen D.   +9 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Armed conflict intensity and inequalities in tuberculosis outcomes in Colombia municipalities, 2008-2019. [PDF]

BMJ Glob Health
Valencia-Aguirre S, Castañeda-Orjuela CA, Gutiérrez-Clavijo JC, Cotes-Cantillo K, Garcia-Basteiro AL.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Notification

Leprosy Review, 2018
openaire   +2 more sources

Association between partner treatment and repeat sexually transmitted infections positivity in pregnant women in East London, South Africa. [PDF]

Sex Transm Infect
Mdingi MM, Gigi RMS, Babalola CM, Taylor C, Muzny CA, Medina Marino A, Klausner JD, Peters RPH.   +7 more
europepmc   +1 more source