Results 141 to 150 of about 210,426 (300)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Canadian Journal of Applied Linguistics, 2015 Although grammars and teaching materials generally present the subjunctive-indicative contrast as being meaningful and categorical, much evidence exists to suggest that mood distinction in modern Hexagonal French is variable, with both the indicative and
Aarnes Gudmestad, Amanda Edmonds
doaj
Aplicació de nous materials i formats amb propietats millorades per a l'anàlisi de drogues
, 2021 Aquesta Tesi Doctoral està dividida en tres blocs principalment. El primer bloc, a partir d’una recerca bibliogràfica, fa un recull de les publicacions més destacades que fan ús de materials intel·ligents per al tractament de mostra abans d’una determinació mitjançant IMS.
openaire +1 more source
The Mahāvastu and the Vinayapiṭaka of the Mahāsāṃghika-Lokottaravādins [PDF]
, 2012 International ...
Tournier, Vincent
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
El gravat calcogràfic: nous procediments i materials més sostenibles (2008)
, 2008 Recull de nous procediments i materials menys tòxics i alternatius als mètodes tradicionals de gravat calcogràfic d'incisió indirecta.
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, 2022 This book is inspired by the quest for the proper function of Aristotle’s active intellect presented in "De Anima 3.5". The urge to grasp its essence has always driven philosophy ahead. Nevertheless, the true nature of nous poitikos remains far from being grasped. I will not unravel it here either, I am afraid. My aim is far more modest: to get through
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Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Nou portal d'accés als materials en obert de la UdG: DUGi 2.0
, 2013 La Biblioteca de la Universitat de Girona és l'encarregada de coordinar els repositoris digitals de la Universitat. A l'inici el repositori neix de la necessitat de difondre i preservar tota la recerca de la Universitat, però mica en mica el projecte va creixent i es creen diferents repositoris per a diferents tipus de continguts.
openaire +3 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source