Results 81 to 90 of about 38,174 (285)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Els nous materials s'inspiren en taurons i flors
Els nous materials sintètics, els més revolucionaris, s"inspiraran en la natura, capaç de crear per ella mateixa estructures amb propietats ...
Bueno i Torrens, David, 1965-
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Introduction. Inter-arm blood pressure difference (IAD) is a well-established clinical practice worldwide. However, the relationship between IAD and cardiovascular disease is not well known.
Fatouma Sall +4 more
doaj +1 more source
El caràcter transfigurable dels objectes digitals
A causa de l'augment d'internet i del que és digital, cada vegada hi ha més patrimoni cultural que adopta la forma d'operacions basades en les TIC, cosa que contradiu les pràctiques i els arxius tradicionals.
Attila Márton
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Les matériaux à base cimentaire, lorsqu’ils sont soumis à des températures élevées, voient leurs caractéristiques mécaniques diminuer. La fissuration de surface entraîne notamment une chute de la résistance en flexion très sensible à l’état de surface ...
Jauberthie R. +3 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Access and Advocacy: Text & Data Mining and DMCA §1201
Significant work in DH has focused on access, labor, and infrastructure. They fundamentally shape the field, from who is included to what we study (for example, see Graban et al 2019, McGrail et al 2022, and Losh and Wernimont 2018). Often less discussed
Lauren Tilton, Quinn Dombrowski
doaj +2 more sources

