Results 101 to 110 of about 38,174 (285)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A study of methods of evaluating multimedia materials for language learning [PDF]

open access: yes
There is a long tradition of paper based materials evaluation in ELT, but at this juncture, a scarcity of studies on ELT Multimedia (MM) materials evaluation.
Sherazi, Saima Nawaz
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Mechanisms of language computing and areas of its use

open access: yesLangues & Cultures
The invention of the computer in the twentieth century, the technology of this device developed over the years, a great development. As for the Arabs, Quranic and religious studies were a forerunner to the use of linguistic computing technology, as that
Amin ALIOUA , Khadidja BENKOUIDER
doaj  

Des goûts et des couleurs. Chronologie relative e£ identité culturelle à travers l'analyse des peintures schématiques du Néolithique dans le sud de la France

open access: yesZephyrus, 2009
RÉSUMÉ: Les figures peintes, attribuées au Néolithique, que nous observons sur les parois des abris, ne représentent souvent qu'une partie de l'iconographie initiale.
Philippe HAMEAU
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Materials porosos per liofilització : els liogels [PDF]

open access: yes, 2009
En aquest treball sobre materials porosos obtinguts per liofilització, s'ha demostrat que es poden produir materials anàlegs als aerogels de sílice mitjançant un procés de congelació i posterior sublimació.
Pons Ràfols, Antoni   +1 more
core  

Biodegradació de nous materials segons la norma 14855

open access: yes, 2018
Des del seu origen a la primera meitat del segle XX, els plàstics han anat prenent cada cop més protagonisme a les nostres vides, generant en conseqüència cada cop més quantitat de residus plàstics arreu del món. Una de les principals problemàtiques que aquests presenten és la seva incapacitat de degradar-se, fet que provoca la seva acumulació a ...
openaire   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy