Results 131 to 140 of about 22,423,968 (289)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Few-Shot Remote Sensing Novel View Synthesis with Geometry Constraint NeRF

Guidance, Navigation and Control
Novel View Synthesis (NVS) is an important task for 3D interpretation in remote sensing scenes, which also benefits vicinagearth security by enhancing situational awareness capabilities.
Jiaming Kang, Keyan Chen, Zhengxia Zou, Zhenwei Shi   +3 more
doaj   +1 more source

Novel UAV-based 3D reconstruction using dense LiDAR point cloud and imagery: A geometry-aware 3D gaussian splatting approach

International Journal of Applied Earth Observations and Geoinformation
The emergence of 3D Gaussian Splatting (3DGS) has recently marked a transformative shift in the realms of 3D representation, efficient rendering, and novel view synthesis.
Kai Qin, Jing Li, Sisi Zlatanova, Haitao Wu, Yin Gao, Yuchen Li, Sizhe Shen, Xiangjun Qu, Zhiyuan Yang, Zhenxin Zhang, Banghui Yang, Shaoyi Wang   +11 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Epipolar-Free 3D Gaussian Splatting for Generalizable Novel View Synthesis [PDF]

Generalizable 3D Gaussian splitting (3DGS) can reconstruct new scenes from sparse-view observations in a feed-forward inference manner, eliminating the need for scene-specific retraining required in conventional 3DGS.
Luo, Yawei, Min, Zhiyuan, Sun, Jianwen, Yang, Yi   +3 more
core   +1 more source

NIRGB‐GS: Near‐Infrared Assisted Low‐Light Scene Reconstruction and Enhancement via Gaussian Splatting

Advanced Intelligent Systems
3D Gaussian Splatting (3DGS) has emerged as a powerful framework for scene reconstruction and novel view synthesis for normal‐light and illumination‐consistent scenes.
Chengyun Yang, Yi Zhang, Yu Lei, Qiaofeng Li   +3 more
doaj   +1 more source

Image Compression Using Novel View Synthesis Priors

IEEE Journal of Oceanic Engineering
Real-time visual feedback is essential for tetherless control of remotely operated vehicles, particularly during inspection and manipulation tasks. Though acoustic communication is the preferred choice for medium-range communication underwater, its limited bandwidth renders it impractical to transmit images or videos in real-time.
Luyuan Peng, Mandar Chitre, Hari Vishnu, Yuen Min Too, Bharath Kalyan, Rajat Mishra, Soo Pieng Tan   +6 more
openaire   +3 more sources

Novel view synthesis

, 2007
Imagine taking a few pictures of a scene with a camera at several different poses, can we generate a novel image that corresponds to a virtual viewpoint where no real camera has captured an image? This is the topic of novel view synthesis.
Wang, Zhe
core