Results 61 to 70 of about 1,890,470 (317)

New Isocoumarins and Related Metabolites from

Natural Product Communications, 2016
Two new isocoumarin derivatives, talaisocoumarins A ( 1 ) and B ( 2 ), and three new related metabolites, talaflavuols A-C ( 3-5 ) were isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13.
Jun-Wei He, Huai-Shuang Xu, Li Yang, Wei-Wei He, Chuan-Xi Wang, Feng Lin, Yang-Yun Lian, Bo-Hang Sun, Guo-Yue Zhong   +8 more
doaj   +1 more source

Structure shapes the representation of a novel category.

Journal of Experimental Psychology: Learning, Memory, and Cognition, 2021
Concepts contain rich structures that support flexible semantic cognition. These structures can be characterized by patterns of feature covariation: certain clusters of features tend to occur in the same items (e.g., feathers, wings, can fly). Existing computational models demonstrate how this kind of structure can be leveraged to slowly learn the ...
Sarah Solomon, Anna Schapiro
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Novel electrode structure for DMFC operated with liquid methanol

, 2006
Novel electrode structures for the direct methanol fuel cell (DMFC) based on Ti mesh are reported. A new anode with a hydrophilic structure prepared by coating Pt-Ru catalyst on Ti mesh using thermal decomposition showed a performance comparable to that ...
Zhu, FY, Shao, ZG, Shao, Z.-G., Zhu, F., Christensen, P.A., Christensen, PA, 邵志刚, Lin, W.-F., Li, MQ, Zhang, H., Lin, WF, Li, M., Zhang, HM   +12 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Novel Method for Accurate One-dimensional Protein Structure Prediction Based on Fragment Matching

, 2010
Motivation: The precise prediction of one-dimensional (1D) protein structure as represented by the protein secondary structure and 1D string of discrete state of dihedral angles (i.e.
Hovmöller, Sven,, Shu, Nanjiang,, Zhou, Tuping,   +2 more
core   +1 more source

Transfer RNAs with novel cloverleaf structures [PDF]

Nucleic Acids Research, 2016
We report the identification of novel tRNA species with 12-base pair amino-acid acceptor branches composed of longer acceptor stem and shorter T-stem. While canonical tRNAs have a 7/5 configuration of the branch, the novel tRNAs have either 8/4 or 9/3 structure.
Mukai, Takahito, Vargas-Rodriguez, Oscar, Englert, Markus, Tripp, H James, Ivanova, Natalia N, Rubin, Edward M, Kyrpides, Nikos C, Söll, Dieter   +7 more
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source