Results 41 to 50 of about 170 (132)
Aims The hollow‐fibre system for tuberculosis (HFS‐TB) is a preclinical model qualified by the European Medicines Agency to underpin the anti‐TB drug development process. It can mimic in vivo pharmacokinetic (PK)–pharmacodynamic (PD) attributes of selected antimicrobials, which could feed into in silico models to inform the design of clinical trials ...
Diana A. Aguilar‐Ayala +10 more
wiley +1 more source
Non‐m6A RNA modifications in haematological malignancies
Non‐m6A RNA modifications play critical roles in haematological malignancies. Gaps exist in understanding of non‐m6A modifications and their regulatory mechanisms in blood cancers. Emerging studies show non‐m6A modification regulators as potential prognostic markers and therapeutic targets in blood malignancies.
Meiling Chen +4 more
wiley +1 more source
Infinito y sustracción en "Qué hacer" de Pablo Katchadjian: lo novelesco en el horizonte neoliberal
La novela experimental Qué hacer (2010) de Pablo Katchadjian está tramada por un procedimiento de repetición y combinatoria que monta, de modo imprevisible y desenfrenado, diferentes escenarios, objetos, acciones y personajes.
Victoria Cóccaro
doaj
Liu et al. identify that YBX1, an m5C reader protein, is upregulated in ESCC tissues. Further, YBX1 promotes ESCC progression by stabilizing SMOX mRNA and consequently activating the mTOCR1 signaling pathway in an NSUN2‐mediated m5C modification‐dependent manner.
Liwen Liu +12 more
wiley +1 more source
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis
Inflammatory retinal microglia with high expression of Cd74 and Ccl5 are identified at the disease peak of experimental autoimmune uveitis (EAU) by single‐cell RNA sequencing. Targeting Cd74 and Ccl5 effectively alleviated microglial activation and disease phenotype in the EAU model .
Jiangyi Liu +9 more
wiley +1 more source
“Our study offers insight into…” Rhetorical promotion in English and Spanish conference abstracts
Abstract The conference abstract (CA) is an important promotional academic genre that allows scholars to introduce their research to their peers as a conference presentation if the proposal is accepted by the reviewing gatekeepers. However, few studies have explored the CA in specific disciplines and no studies have examined this genre from an ...
Pedro Martín, Sally Burgess
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THE ORIGINS OF FLANN O’BRIEN’S AT SWIM- TWO-BIRDS
At Swim-Two-Birds, la primera novela de Flann O'Brien publicada en 1939, ha sido generalmente considerada como la obra maestra de Flann O'Brien debido a su narración espontánea y su estilo experimental.
Germán Asensio Peral
doaj
Creation, intersubjectivity and the novel: Unamuno on life in Cómo se hace una novela
Abstract This article shows that, in Miguel de Unamuno, both philosophy and literature contribute to an intellectual project that has to do with life. I will argue that Unamuno, in Cómo se hace una novela, presents a philosophy of life that understands human life as an intersubjective creation.
Katrine Helene Andersen
wiley +1 more source
Reseña - Jorge Bracamonte: Por una teoría desde la novela experimental argentina hasta 1980
Jorge Bracamonte teoriza alrededor de las problemáticas de la novela experimental, de ruptura, de vanguardia, realizando un recorrido a través de una selección de obras, de autores de la literatura argentina, retrocediendo su mirada a décadas de grandes cambios en el siglo XX, a partir de los ’40, de los ’60 hasta 1980, como bien refiere en el título ...
openaire +1 more source
Un prefacio de la autora enumera características, objetivos y pasos metodológicos de "un estudio ecléctico" cuyo corpus de investigación incluye 62. Modelo para armar (1968); Libro de Manuel (1973), Los autonautas de la cosmopista (1984), obras publicadas por Cortázar después de Rayuela (1963).
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