Results 101 to 110 of about 210,711 (296)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Codification of Justinian: legal and technical analysis
Юридический вестник Самарского университетаBased on the historical and legal approach, the legal and technical features of the codification, developed on the initiative of Emperor Justinian I, are analyzed.
S. V. Elekina
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Humour in the novel 1800-1850 : the moral vision and the autonomous imagination [PDF]
This thesis attempts to trace the development of two kinds of humorous sensibility in the fiction of the period 1800-1850, and to analyse the tensions between them.
Fairclough, Peter
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Watching As The World Turns: Performance, Everyday Life, and the Self in the Novels of David Foster Wallace [PDF]
, 2015 This thesis examines manifestations of performance in the novels of David Foster Wallace. It argues that as Wallace engages with the theme of performance he concurrently addresses the related topics of everyday life and the self.
South, Daniel
core
A Novel Illness, a Novel Communications Approach [PDF]
HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery, 2020 Chisholm, Mary +5 more
openaire +2 more sources