Results 91 to 100 of about 219,041 (325)
Advanced Science, EarlyView.Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source
1-Safe Petri nets and special cube complexes: equivalence and applications
, 2019 Nielsen, Plotkin, and Winskel (1981) proved that every 1-safe Petri net $N$ unfolds into an event structure $\mathcal{E}_N$. By a result of Thiagarajan (1996 and 2002), these unfoldings are exactly the trace regular event structures.
Chalopin, Jérémie, Chepoi, Victor
core +3 more sources
Loss of ARID1A promotes proliferation, migration and invasion via the Akt signaling pathway in NPC
Cancer Management and Research, 2019 Background: AT-rich interactive domain-containing protein 1A (ARID1A) is a member of the switch/sucrose nonfermentable chromatin remodeling complex, which has been observed to be mutated in various tumors.
Yang Yang +7 more
semanticscholar +1 more source
Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition
Advanced Science, EarlyView.Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han +9 more
wiley +1 more source
Human Polycomb Protein 2 (hPC2) as a Novel Independent Prognostic Marker in Nasopharyngeal Carcinoma
Cancer Management and Research, 2021 Mei Wu,1 Li Yang,1 Xiaojuan Hou,1 Ziyuan Wang,1 Jianqing Zhang2 1Diagnosis and Treatment Center of Otorhinolaryngology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, Xinjiang, People’s Republic of China; 2Department of ...
Wu M, Yang L, Hou X, Wang Z, Zhang J
doaj
The Empirical (ir)Relevance of the New Keynesian Phillips Curve [PDF]
We give an appraisal of the New Keynesian Phillips curve (NPC) as an empirical model of European inflation. We show that existing evidence reported in favour of the NPC on Euro-area and country data is due to a corroborative research strategy.
Eilev S. Jansen +2 more
core
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
Advanced Science, EarlyView.OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Structure of wavefunctions in (1+2)-body random matrix ensembles
, 2001 Abstrtact: Random matrix ensembles defined by a mean-field one-body plus a chaos generating random two-body interaction (called embedded ensembles of (1+2)-body interactions) predict for wavefunctions, in the chaotic domain, an essentially one parameter ...
B. Georgeot +29 more
core +1 more source
Advanced Science, EarlyView.Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao +8 more
wiley +1 more source
The empirical relevance of the New Keynesian Phillips curve. [PDF]
The dynamic properties of the The New Keynesian Phillips curve (NPC) is analysed within the framework of a small system of linear difference equations. We evaluate the empirical results of existing studies which uses `Euroland' and US data.
Eilev S. Jansen +2 more
core