Results 251 to 260 of about 114,500 (312)

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Single-cell transcriptomics and functional validation reveal a TUBB4B-associated malignant epithelial state in nasopharyngeal carcinoma. [PDF]

J Transl Med
Chen X, Liao W, Xu M, Peng B, Pan F, Xiao Y, Chen D, Wu Y, Hu R, Qin H, Feng G, Zheng Y, Du H, Zhang Q, Chen G, Song L, Zhang X, Lu Y, Xie J.   +18 more
europepmc   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Preterm birth disrupts nephron progenitor cell dynamics predisposing to renal disease. [PDF]

iScience
Amleh A, Piran M, Moreau JLM, Schnapp A, Combes AN, Volovelsky O, Nechama M.   +6 more
europepmc   +1 more source

Veterinary nurses report good interprofessional collaboration with veterinarians, as measured by the Nurse–Physician Collaboration Scale

Veterinary Record, EarlyView.
Abstract Background Veterinary practices provide exceptional patient care and client support when there is effective teamwork between veterinary nurses and veterinarians. However, the frequency of this interprofessional collaboration has not been measured. Methods A cross‐sectional online survey, using the Nurse‒Physician Collaboration Scale to measure
Samantha J. Fontaine, Kelly Cadman, Euan D. Bennet, Dorothy E. F. McKeegan   +3 more
wiley   +1 more source

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy. [PDF]

Oncol Lett
Yang SC, Ho CH, Shieh LT, Lee SW, Chen CC, Ho SY.   +5 more
europepmc   +1 more source

Multi‐Sequence Fusion MRI Deep Learning Models for Discrimination of Recurrent Nasopharyngeal Carcinoma and Osteoradionecrosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives To develop a multi‐sequence fusion model based on MRI images to differentiate between recurrent nasopharyngeal carcinoma (rNPC) and osteoradionecrosis (ORN) in patients with nasopharyngeal carcinoma (NPC) after radiotherapy, and to evaluate its diagnostic performance.
Wen‐Tao Gong, Xue‐Li Liu, Xiao Chen, Zhen Li, Ming‐Yan Qiu, Shang Shi, Xuan‐Yu Zhao, Li Wang, Quan Liu, Xi‐Cai Sun, Yu‐Xuan Shi, Hong‐Meng Yu   +11 more
wiley   +1 more source

Systematic Review of AI-Driven Applications for Screening Nasopharyngeal Carcinoma Using MRI. [PDF]

J Magn Reson Imaging
Wong LM, Leung HS, Yang Z, Tsang YM, Chan YT, So TY, King AD, Ai QYH.   +7 more
europepmc   +1 more source

Yeast Knockout Strain Collection: Driving Functional Genomics, Biotechnological Applications and Human Disease Research

Yeast, EarlyView.
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley   +1 more source

EV-transferred miR-7111-3p inhibits malignant phenotypes and tumor growth in nasopharyngeal carcinoma via targeting APP-regulated epithelial-mesenchymal transition. [PDF]

J Transl Med
Huang H, Xiao Z, Chen W, Li Z, Chen X, Yang X, Chen X, Luo Z, Chen H, Qu S.   +9 more
europepmc   +1 more source