Results 61 to 70 of about 219,041 (325)
Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Goals in the Management of Regional Finances: А Logical-Content Analysis of State Programs
Управленческие науки, 2019 The transition to the formation of budgets on the basis of the program-target method is one of the significant achievements of the budget policy pursued in russia in terms of increasing the budget expenditures efficiency.
R . V. Erzhenin
doaj +1 more source
A simplified point-of-service model for hepatitis C in people who inject drugs in South Africa
Harm Reduction Journal, 2023 Background Globally, 9% of people who inject drugs (PWID), a key hepatitis C-infected population, reside in sub-Saharan Africa. In South Africa, hepatitis C seroprevalence in PWID is high.
Elaine Saayman +3 more
doaj +1 more source
Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore [PDF]
, 2004 Resident integral proteins of the inner nuclear membrane (INM) are synthesized as membrane-integrated proteins on the peripheral endoplasmic reticulum (ER) and are transported to the INM throughout interphase using an unknown trafficking mechanism.
Gerace, Larry +3 more
core +3 more sources
Advanced Functional Materials, EarlyView.This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source
Drug Design, Development and Therapy, 2021 Junwu Lin,1,* Hong Qin,2,* Yue Han,3 Xinghua Li,4 YuJuan Zhao,5 Guangsheng Zhai6 1Department of Otolaryngology, Central Hospital, Qingdao, Shandong, People’s Republic of China; 2Department of Otolaryngology, Women and Children’s Hospital ...
Lin J +5 more
doaj
Ecology and Evolution, 2023 Abiotic factors are usually considered key drivers of species distribution at macro scales, while biotic interactions are mostly used at local scales.
Francesca Cosentino +3 more
doaj +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Introducing the South African Rare Diseases Access Initiative
South African Medical Journal, 2023 -
H Malherbe
doaj +1 more source
Advanced Functional Materials, EarlyView.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source