Results 41 to 50 of about 76,371 (261)

Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

open access: yesCell Reports, 2015
Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos. During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic ...
Takashi Onikubo   +11 more
doaj   +1 more source

NIPA (Nuclear Interaction Partner of ALK) Is Crucial for Effective NPM-ALK Mediated Lymphomagenesis

open access: yesFrontiers in Oncology, 2022
The NPM-ALK fusion kinase is expressed in 60% of systemic anaplastic large-cell lymphomas (ALCL). A Nuclear Interaction Partner of ALK (NIPA) was identified as a binding partner of NPM-ALK.
Stefanie Kreutmair   +20 more
doaj   +1 more source

New Public Management (NPM) as an Effort in Governance

open access: yesJurnal Manajemen Pelayanan Publik, 2020
New Public Management (NPM) is an approach in public administration that applies knowledge and experience gained in the world of management and other disciplines to improve the efficiency and effectiveness of public service performance in modern ...
Charity Latanza Indahsari, S. Raharja
semanticscholar   +1 more source

The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation

open access: yesCell & Bioscience, 2019
Background Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in telomerase loading to telomeres.
Sai-Tim Ho   +4 more
doaj   +1 more source

Blind Estimation Versus Direct Measurement of the Arterial Input Function in Dynamic Contrast-Enhanced MRI of the Breast. [PDF]

open access: yesMagn Reson Med
PurposeAccurate arterial input functions (AIFs) are essential for quantitative dynamic contrast‐enhanced (DCE) MRI, yet direct measurement is challenging and population‐averaged AIFs neglect patient‐specific variability. Blind deconvolution provides an alternative by estimating patient‐specific AIFs directly from tissue data, up to a scale factor. This
Cray JL   +4 more
europepmc   +2 more sources

On the Impact of Security Vulnerabilities in the npm Package Dependency Network

open access: yesIEEE Working Conference on Mining Software Repositories, 2018
Security vulnerabilities are among the most pressing problems in open source software package libraries. It may take a long time to discover and fix vulnerabilities in packages.
Alexandre Decan   +2 more
semanticscholar   +1 more source

On the Diversity of Software Package Popularity Metrics: An Empirical Study of npm [PDF]

open access: yesIEEE International Conference on Software Analysis, Evolution, and Reengineering, 2019
Software systems often leverage on open source software libraries to reuse functionalities. Such libraries are readily available through software package managers like npm for JavaScript.
Ahmed Zerouali   +3 more
semanticscholar   +1 more source

Pengaruh Return on Asset (ROA), Current Ratio (CR), Net Profit Margin (NPM) dan Inflasi terhadap Harga Saham (Studi Kasus PT Kalbe Farma, Tbk. Periode Tahun 2001–2014)

open access: yesJurnal Maksipreneur: Manajemen, Koperasi, dan Entrepreneurship, 2015
This study wasconducted toexamine the effect ofROA, CR, NPM andinflationon the price of the shares of PT KalbeFarma. Thisresearchusescasestudyperiodof 2001-2014.The analysis usedis multiple regression withSPSS.From the results of the analysis indicate ...
Subarjo Subarjo
doaj   +1 more source

Association between early nonpharmacological management and follow-up for low back pain in the veterans health administration

open access: yesNorth American Spine Society Journal, 2023
Background: Low back pain (LBP) is a common reason individuals seek healthcare. Nonpharmacologic management (NPM) is often recommended as a primary intervention, and earlier use of NPM for LBP shows positive clinical outcomes. Our purpose was to evaluate
Brian C. Coleman, DC, MHS   +4 more
doaj   +1 more source

On the Evolution of Technical Lag in the npm Package Dependency Network [PDF]

open access: yesIEEE International Conference on Software Maintenance and Evolution, 2018
Software packages developed and distributed through package managers extensively depend on other packages. These dependencies are regularly updated, for example to add new features, resolve bugs or fix security issues.
Alexandre Decan   +2 more
semanticscholar   +1 more source

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