Results 61 to 70 of about 396,691 (306)
eLife, 2018 Dopamine (DA) neurons of the ventral tegmental area (VTA) integrate cholinergic inputs to regulate key functions such as motivation and goal-directed behaviors.
Romain Durand-de Cuttoli +12 more
doaj +1 more source
Dopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task
Cell Reports, 2023 Summary: The neural mechanisms by which animals initiate goal-directed actions, choose between options, or explore opportunities remain unknown. Here, we develop a spatial gambling task in which mice, to obtain intracranial self-stimulation rewards, self-
Elise Bousseyrol +11 more
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Comparison of Algorithms for Clustering Incomplete Data
Foundations of Computing and Decision Sciences, 2014 The missing values are not uncommon in real data sets. The algorithms and methods used for the data analysis of complete data sets cannot always be applied to missing value data.
Matyja Artur, Siminski Krzysztof
doaj +1 more source
EPR and Structural Characterization of Water-Soluble Mn2+-Doped Si Nanoparticles. [PDF]
, 2017 Water-soluble poly(allylamine) Mn2+-doped Si (SiMn) nanoparticles (NPs) were prepared and show promise for biologically related applications. The nanoparticles show both strong photoluminescence and good magnetic resonance contrast imaging.
Atkins, Tonya M +6 more
core +3 more sources
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Scientific Reports, 2023 The severe accident scenario propagation studies of nuclear power plants (NPPs) have been one of the most critical factors in deploying nuclear power for decades.
K. Hossny, W. Villanueva, H. D. Wang
doaj +1 more source
Yeast-derived biosynthesis of silver/silver chloride nanoparticles and their antiproliferative activity against bacteria [PDF]
, 2016 Here, we provide the first evidence of yeast strains assisted Ag/AgCl-NPs production in vitro. The formed nanoparticles were characterized by spectroscopic and electron microscopy approaches. UV-vis supported the biosynthesis. TEM analysis evidenced that
Almeida-Paes, Rodrigo +8 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Unravelling the Correlation of Electronic Structure and Carrier Dynamics in CuInS\u3csub\u3e2\u3c/sub\u3e Nanoparticles [PDF]
, 2017 In this work, we report the direct correlation of photoinduced carrier dynamics and electronic structure of CuInS2 (CIS) nanoparticles (NPs) using the combination of multiple spectroscopic techniques including steady-state X-ray absorption spectroscopy ...
Hu, Wenhui +7 more
core +1 more source