Results 181 to 190 of about 40,265 (264)
Brain Pathology, EarlyView.We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour +10 more
wiley +1 more source
Dust Mite-Specific IgE in Nasal Lavage Fluid During Natural Allergen Exposure and After Nasal Provocation Test in Subjects with Suspected Local Allergic Rhinitis. [PDF]
Life (Basel)Mortada MM +5 more
europepmc +1 more source
Brain Pathology, EarlyView.Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen +8 more
wiley +1 more source
Efficacy of ultrasound-guided combined sphenopalatine and stellate ganglion block in the treatment of allergic rhinitis. [PDF]
Quant Imaging Med SurgYan Z, Yang M, Pang Y, Ma B, Li T.
europepmc +1 more source
Developmental Medicine &Child Neurology, EarlyView.This systematic review identifies barriers and facilitators to implementing early motor interventions for young children with non‐progressive motor disorders. Framework‐informed strategies, including workforce development, locally supported digital approaches, and family‐centred support, may enhance scalability, accessibility, and sustainability across
Nahdiah Purnamasari +4 more
wiley +1 more source
Interventions for binge eating disorder in adults with type 2 diabetes: A systematic review
Diabetic Medicine, EarlyView.Abstract Aims Binge eating disorder frequently co‐occurs with type 2 diabetes, creating a dual burden that may complicate both psychological well‐being and glycaemic management. Evidence on the effectiveness of health interventions in this population is limited.
Pernille Fiil Nybo +4 more
wiley +1 more source
Embedding Patient and Public Involvement in Health Professions Education: Bridging Novelty and Normalisation. [PDF]
Clin TeachPaxino J +5 more
europepmc +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Natural procreative technology (NaProTechnology) for infertility: take-home baby rate and clinical outcomes in a 5-year single-center cohort of 1,310 couples. [PDF]
Front Reprod HealthSánchez-Méndez JI +10 more
europepmc +1 more source
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source