Results 181 to 190 of about 52,027 (252)

Deformation, Creep, and Dynamics in Glassy Ionomers

open access: yesJournal of Polymer Science, EarlyView.
Ionic architecture tunes the inelastic deformation of glassy ionomers. Simulations show that ionic associations leave the small‐strain elastic baseline nearly unchanged, but strongly reinforce yielding, strain hardening, and creep resistance. Polyampholyte architectures suppress nonaffine mobility and stress‐induced fluidization most effectively by ...
Nazanin Sadeghi, Fardin Khabaz
wiley   +1 more source

An (αβ)2 Architecture of the Arabidopsis thaliana tRNA Splicing Endonuclease Complex: Structural Modeling and Evolutionary Analyses

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman   +2 more
wiley   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

Experiences of Augmentative and Alternative Communication use in School: A Qualitative Evidence Synthesis Protocol. [PDF]

open access: yesHRB Open Res
Byrnes C   +6 more
europepmc   +1 more source

Structural and Stability Analysis of de Novo Designed Proteins Incorporating a Plant Self‐Incompatibility Motif

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi   +7 more
wiley   +1 more source

Molecular Interactions of Viral Insulin/IGF‐Like Peptides With Zebrafish Receptors

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Signaling through the insulin receptor (IR) and the type 1 insulin‐like growth factor receptor (IGF1R) is modulated by secreted hormones and growth factor ligands (e.g., insulin and insulin‐like growth factor 1, IGF1). Impaired signaling in these receptors often leads to diabetes and oncogenic diseases.
Lev Levintov, Harish Vashisth
wiley   +1 more source

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