Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Independent evaluation of the North East Hampshire and Farnham Vanguard. Using the Normalisation Process Theory [NPT] framework to evaluate a new care model [NCM]: the Happy Healthy at Home [HHH] Enhanced Recovery at Home [ER@H] [PDF]
, 2017 Catherine Matheson-Monnet
openalex
AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source
Delivering an exploratory near-peer teaching pilot in general practice: a qualitative study of the experiences of GP speciality trainees and medical students. [PDF]
BMC Med EducCarson J, Emery H, Taggar J, Wilson E.
europepmc +1 more source
Addressing Low E/S and N/P Ratio Challenges in Li–S Batteries with a Multifunctional Interlayer
Small, EarlyView.With its multifunctional properties—effective shuttle effect inhibition and high ionic conductivity enabled by the sulfonic acid groups of PFSA, together with superior electrical conductivity from CNT and PEDOT:TCB for dead‐sulfur reactivation—the ultrathin and lightweight PCP interlayer enables outstanding Li–S battery performance under practical low ...
Cinthya Paulina +9 more
wiley +1 more source
Attainment of medical student learning outcomes following general practice specialty trainee supervision: a pilot study. [PDF]
BJGP OpenCarson J +7 more
europepmc +1 more source
Analytical analysis of Quasi-Saturation Effect in PT and NPT IGBTs
, 2002 S. Pittet, Alfred Rufer
openalex +1 more source
Factors Associated with Early Discontinuation of Foslevodopa/Foscarbidopa in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Keita Kakuda +7 more
wiley +1 more source