The predictive value of necroptosis-related lncRNAs in prostate cancer prognosis and their potential to distinguish between cold and hot tumors [PDF]
Frontiers in Cell and Developmental BiologyBackgroundProstate cancer (PCa) is frequently associated with poor prognosis, and immunotherapy has shown limited efficacy. This study aimed to identify novel necroptosis-related long non-coding RNAs (lncRNAs) that could predict patient outcomes and ...
Ke Zhang +5 more
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Retracted: NR2F1-AS1 Acts as an Oncogene in Breast Cancer by Competitively Binding with miR-641. [PDF]
J Healthc Eng, 2023 Healthcare Engineering JO.
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Exploring Long Noncoding RNAs as Regulators of Tumor Ferroptosis: Advances and Challenges. [PDF]
Cancer SciLong noncoding RNAs (lncRNAs) play pivotal roles in regulating gene expression and are closely associated with cancer progression, prognosis, and therapeutic resistance. This review highlights recent advancements in understanding how lncRNAs modulate ferroptosis, a regulated form of cell death characterized by iron‐dependent lipid peroxidation ...
Li G, Wang B, Ye L, Wang G.
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Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis. [PDF]
Int J Med Sci, 2023 Abstract Background: Long noncoding RNAs (LncRNAs) has been demonstrated to have a considerable effect on tumor metastasis and are aberrently expressed in a variety of cancers. Nevertheless, its role in breast cancer (BC) remains incompletely inventoried.Methods: The microarray assay of differentially expressed lncRNAs in epithelial-mesenchymal
Zhai D +7 more
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The short peptide encoded by long non-coding RNA RNF217-AS1 inhibits stomach cancer tumorigenesis, macrophage recruitment, and pro-inflammatory responses [PDF]
Amino AcidsCertain long non-coding RNAs (lncRNAs) have potential peptide-coding abilities. Here, the role and molecular basis of the RNF217-AS1-encoded peptide in stomach cancer (SC) tumorigenesis were explored.
Qi Ma +5 more
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The Effect and Mechanism of lncRNA NR2F1-As1/miR-493-5p/MAP3K2 Axis in the Progression of Gastric Cancer. [PDF]
J Oncol, 2021 Background. LncRNA NR2F1-AS1 has been identified as an oncogene in some human tumors, such as breast cancer, nonsmall cell lung cancer, and esophageal squamous cell carcinoma. Nonetheless, whether NR2F1-AS1 is involved in the progression of gastric cancer (GC) remains unknown. Methods.
Liao X, Wen L, Luo L.
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NR2F1-AS1 Acts as an Oncogene in Breast Cancer by Competitively Binding with miR-641. [PDF]
J Healthc Eng, 2022 Background. Long noncoding RNA (lncRNA) NR2F1-AS1 has been previously reported to be dysregulated in human cancers and implicated in the tumorigenesis and development of tumors. In this research, we detected the expression level and biological function of NR2F1-AS1 in breast cancer (BC). Methods. The expression of NR2F1-AS1 in BC tissues and cell lines
Zhong Y, Zeng W, Zeng W.
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Long non-coding RNA NR2F1-AS1: an increasingly significant LncRNA in human cancers. [PDF]
J Physiol BiochemAbstract Long non-coding RNAs (lncRNAs), defined as transcripts exceeding 200 nucleotides without protein-coding potential, have emerged as pivotal regulators in diverse physiological and pathological processes, particularly in tumorigenesis. Among them, NR2F1-AS1, a recently characterized lncRNA, has garnered growing attention due to
Yao Q +5 more
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Long Noncoding RNA NR2F1-AS1 Enhances the Migration and Invasion of Hepatocellular Carcinoma via Modulating miR-642a/DEK Pathway. [PDF]
J Oncol, 2021 Purpose. Hepatocellular carcinoma (HCC), a malignant tumor that exists worldwide, has a high morbidity and mortality rate. Previous studies have reported that lncRNA NR2F1-AS1 plays a critical role in several cancers. Here, we aimed to investigate the biological function of NR2F1-AS1 and its molecular mechanism in the migration and invasion of HCC ...
Xu Y, Han C, Sun J, Zhao J, Liu Q, An P.
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Long non‑coding RNA NR2F1‑AS1 facilitates the osteosarcoma cell malignant phenotype via the miR‑485‑5p/miR‑218‑5p/BIRC5 axis. [PDF]
Oncol Rep, 2020 Long non‑coding RNA (lncRNA) NR2F1 antisense RNA 1 (NR2F1‑AS1) has been reported to be an oncogene in several cancer types, including osteosarcoma (OS). However, the underlying fundamental molecular mechanism of NR2F1‑AS1 in OS remains largely unknown, which the present study aimed to elucidate.
Jia G, Wang Y, Yu Y, Li Z, Wang X.
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