Results 101 to 110 of about 410,492 (225)

A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans

, 2014
Study Objectives: Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loop-helix family member e41) as causal in a family of short sleepers, who needed just 6 h sleep per night.
Dinges, David F, Kuna, Samuel T., Van Dongen, Hans P A, Tufik, Sergio [UNIFESP], Pack, Allan I., Dinges, David F., Pellegrino, Renata, Pack, Allan I, Pellegrino, Renata [UNIFESP], Tufik, Sergio, Hogenesch, John B, Maislin, Greg, Hakonarson, Hakon, Kavakli, Ibrahim Halil, Van Dongen, Hans P. A., Goel, Namni, Cardinale, Christopher J., Kuna, Samuel T, Hogenesch, John B., Cardinale, Christopher J   +19 more
core   +1 more source

Is sleep affected after microgravity and hypergravity exposure? A pilot study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is known to be affected in space travel and in residents of the international space station. But little is known about the direct effects of gravity changes on sleep, if other factors, such as sleep conditions, are kept constant. Here, as a first exploration, we investigated sleep before and after exposure to short bouts of microgravity ...
Barbara Le Roy, Aurore Jouvencel, Anika Friedl‐Werner, Ludmila Renel, Youcef Cherchali, Raouf Osseiran, Ernesto Sanz‐Arigita, Jean‐René Cazalets, Etienne Guillaud, Ellemarije Altena   +9 more
wiley   +1 more source

Circadian Regulation of Sleep and the Sleep EEG under Constant Sleep Pressure in the Rat

, 2020
Sleep is regulated by homeostatic and circadian processes. Slow wave activity (SWA; 1-4 Hz) in the NREM sleep electroencephalogram (EEG) reflects sleep homeostasis.
Deboer, T, Yasenkov, RV
core  

Reduced NREM sleep instability in children with sleep disordered breathing

, 2007
Study Objectives: To evaluate NREM sleep instability, as measured by the cyclic alternating pattern (CAP), in a cohort of children with mild sleep disordered breathing (SDB) or frank obstructive sleep apnea (OSA) and normal controls.
D. Gozal, VILLA, MARIA PIA, R. Ferri, Oliviero Bruni, MIANO, Silvia, BRUNI, Oliviero, Silvia Miano, David Gozal, Raffaele Ferri, Leila Kheirandish-Gozal, Jacopo Pagani, Maria Pia Villa, L. Kheirandish Gozal   +12 more
core   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini, Sara Alvente, Chiara Berteotti, Viviana Lo Martire, Gabriele Matteoli, Elena Miglioranza, Alessandro Silvani, Giovanna Zoccoli   +7 more
wiley   +1 more source

Homeostatic Sleep Regulation in Adolescents

, 2005
STUDY OBJECTIVES: To examine the effects of total sleep deprivation on adolescent sleep and the sleep electroencephalogram (EEG) and to study aspects of sleep homeostasis.
Jenni, Oskar G; https://orcid.org/, Carskadon, Mary A, Achermann, Peter   +2 more
core   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

Correlations using the NREM-REM sleep cycle frequency support distinct regulation mechanisms for REM and NREM sleep.

, 2002
Polysomnograms of most homeothermic species distinguish two states, rapid eye movement (REM) and non-REM (NREM) sleep. These alternate several times during the night for reasons and following rules that remain poorly understood.
Rivelli, S K, Pelc, Isidore, Le Bon, Olivier, Linkowski, Paul, Hoffmann, Guy, Staner, Luc   +5 more
core   +1 more source