Results 1 to 10 of about 703,277 (252)

Preoperative insomnia exacerbates postoperative sleep fragmentation in elderly arthroplasty patients: a prospective cohort study [PDF]

open access: yesFrontiers in Psychiatry
BackgroundPreoperative insomnia is prevalent among elderly arthroplasty patients, yet its impact on postoperative sleep disturbance (PSD) remains underexplored.
Jiawen Su   +6 more
doaj   +2 more sources

Sleep fragmentation in critically ill children: a review of contributing factors in the pediatric intensive care unit and neurodevelopmental outcomes [PDF]

open access: yesFrontiers in Sleep
Sleep is a critical neurobiological process essential for brain maturation, emotional regulation, cognitive development, and overall organ system homeostasis.
Alana GaHyun Byeon   +8 more
doaj   +2 more sources

Sleep disruption with aging in senescence-accelerated mice-prone 8 (SAMP8) mice and analysis of factors associated with age-related sleep fragmentation using RNA sequencing of the hypothalamus [PDF]

open access: yesNeurobiology of Sleep and Circadian Rhythms
Aging is a risk factor for various disorders, and age-dependent changes in sleep parameters are involved in the pathogenesis of many diseases. Senescence-accelerated mice-prone 8 (SAMP8) have a short lifespan and show a disrupted circadian rhythm ...
Kazuyuki Okamura   +6 more
doaj   +2 more sources

Sleep Fragmentation as a Diagnostic Biomarker of Traumatic Brain Injury [PDF]

open access: yesNeurotrauma Reports
Sleep disturbances are among the most prevalent and persistent consequences of traumatic brain injury (TBI), yet they remain underutilized as clinical indicators of injury status.
Grant S. Mannino   +3 more
doaj   +2 more sources

Timing of outdoor light exposure is associated with sleep-wake consolidation in community-dwelling older men

open access: yesFrontiers in Sleep, 2023
IntroductionA consolidated sleep-wake pattern is essential for maintaining healthy cognition in older individuals, but many suffer from sleep fragmentation that exacerbates age-related cognitive decline and worsens overall mental and physical health ...
Renske Lok   +7 more
doaj   +1 more source

Short-term maintenance on a high-sucrose diet alleviates aging-induced sleep fragmentation in drosophila

open access: yesAnimal Cells and Systems, 2021
Sleep is a fundamental behavior in an animal’s life influenced by many internal and external factors, such as aging and diet. Critically, poor sleep quality places people at risk of serious medical conditions.
Sang Hyuk Lee, Eun Young Kim
doaj   +1 more source

Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway

open access: yesJournal of Neuroinflammation, 2012
Background Sleepiness and cognitive dysfunction are recognized as prominent consequences of sleep deprivation. Experimentally induced short-term sleep fragmentation, even in the absence of any reductions in total sleep duration, will lead to the ...
Ramesh Vijay   +9 more
doaj   +1 more source

Recurrent sleep fragmentation induces insulin and neuroprotective mechanisms in middle-aged flies

open access: yesFrontiers in Aging Neuroscience, 2016
Lack of quality sleep increases central nervous system oxidative stress and impairs removal of neurotoxic soluble metabolites from brain parenchyma. During aging poor sleep quality, caused by sleep fragmentation, increases central nervous system cellular
Michael J Williams   +10 more
doaj   +1 more source

Sleep onset (mis)perception in relation to sleep fragmentation, time estimation and pre-sleep arousal

open access: yesSleep Medicine: X, 2020
Study objective: To elucidate the contribution of time estimation and pre sleep arousal to the component of sleep onset misperception not explained by sleep fragmentation.
Lieke W.A. Hermans   +4 more
doaj   +1 more source

Abnormal Sleep Signals Vulnerability to Chronic Social Defeat Stress

open access: yesFrontiers in Neuroscience, 2021
There is a tight association between mood and sleep as disrupted sleep is a core feature of many mood disorders. The paucity in available animal models for investigating the role of sleep in the etiopathogenesis of depression-like behaviors led us to ...
Basma Radwan   +2 more
doaj   +1 more source

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