Results 1 to 10 of about 703,277 (252)
Preoperative insomnia exacerbates postoperative sleep fragmentation in elderly arthroplasty patients: a prospective cohort study [PDF]
BackgroundPreoperative insomnia is prevalent among elderly arthroplasty patients, yet its impact on postoperative sleep disturbance (PSD) remains underexplored.
Jiawen Su +6 more
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Sleep fragmentation in critically ill children: a review of contributing factors in the pediatric intensive care unit and neurodevelopmental outcomes [PDF]
Sleep is a critical neurobiological process essential for brain maturation, emotional regulation, cognitive development, and overall organ system homeostasis.
Alana GaHyun Byeon +8 more
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Sleep disruption with aging in senescence-accelerated mice-prone 8 (SAMP8) mice and analysis of factors associated with age-related sleep fragmentation using RNA sequencing of the hypothalamus [PDF]
Aging is a risk factor for various disorders, and age-dependent changes in sleep parameters are involved in the pathogenesis of many diseases. Senescence-accelerated mice-prone 8 (SAMP8) have a short lifespan and show a disrupted circadian rhythm ...
Kazuyuki Okamura +6 more
doaj +2 more sources
Sleep Fragmentation as a Diagnostic Biomarker of Traumatic Brain Injury [PDF]
Sleep disturbances are among the most prevalent and persistent consequences of traumatic brain injury (TBI), yet they remain underutilized as clinical indicators of injury status.
Grant S. Mannino +3 more
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IntroductionA consolidated sleep-wake pattern is essential for maintaining healthy cognition in older individuals, but many suffer from sleep fragmentation that exacerbates age-related cognitive decline and worsens overall mental and physical health ...
Renske Lok +7 more
doaj +1 more source
Sleep is a fundamental behavior in an animal’s life influenced by many internal and external factors, such as aging and diet. Critically, poor sleep quality places people at risk of serious medical conditions.
Sang Hyuk Lee, Eun Young Kim
doaj +1 more source
Background Sleepiness and cognitive dysfunction are recognized as prominent consequences of sleep deprivation. Experimentally induced short-term sleep fragmentation, even in the absence of any reductions in total sleep duration, will lead to the ...
Ramesh Vijay +9 more
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Recurrent sleep fragmentation induces insulin and neuroprotective mechanisms in middle-aged flies
Lack of quality sleep increases central nervous system oxidative stress and impairs removal of neurotoxic soluble metabolites from brain parenchyma. During aging poor sleep quality, caused by sleep fragmentation, increases central nervous system cellular
Michael J Williams +10 more
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Study objective: To elucidate the contribution of time estimation and pre sleep arousal to the component of sleep onset misperception not explained by sleep fragmentation.
Lieke W.A. Hermans +4 more
doaj +1 more source
Abnormal Sleep Signals Vulnerability to Chronic Social Defeat Stress
There is a tight association between mood and sleep as disrupted sleep is a core feature of many mood disorders. The paucity in available animal models for investigating the role of sleep in the etiopathogenesis of depression-like behaviors led us to ...
Basma Radwan +2 more
doaj +1 more source

