Results 111 to 120 of about 844,158 (279)

A Centralized SDN Architecture for the 5G Cellular Network

open access: yes, 2018
In order to meet the increasing demands of high data rate and low latency cellular broadband applications, plans are underway to roll out the Fifth Generation (5G) cellular wireless system by the year 2020. This paper proposes a novel method for adapting
Jha, Pranav   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Radio Co-location Aware Channel Assignments for Interference Mitigation in Wireless Mesh Networks

open access: yes, 2015
Designing high performance channel assignment schemes to harness the potential of multi-radio multi-channel deployments in wireless mesh networks (WMNs) is an active research domain.
Kala, Srikant Manas   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A new WPAN Model for NS-3 simulator [PDF]

open access: yes, 2013
International audienceWireless sensor networks are one of the most challenging topics in research world due to the nature of the wireless communication and the constraints related to the sensor’s components. However, this field knows a very fast progress
Chanet, Jean-Pierre   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A Study on Performance of CUBIC TCP and TCP BBR in FANETs

open access: yesمجلة جامعة الزيتونة, 2021
Flying ad-hoc networks (FANETs) recently have paid attention regarding to technological progress in the field of wireless network, it has proposed for various purposes including military, surveillance and monitoring of areas, where it is unreachable by a
Mohamed Alrayes   +3 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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