Results 281 to 290 of about 176,388 (298)

Gastrointestinal and cardiovascular adverse events associated with NSAIDs

Expert Opinion on Drug Safety, 2021
Introduction Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed pharmacological groups, especially in elderly patients. Areas Covered The main GI and CV adverse events associated with NSAID use are reviewed.
M. D. Domper Arnal, G. Hijos-Mallada, Á. Lanas   +2 more
semanticscholar   +1 more source

Non-steroidal anti-inflammatory drugs (NSAIDs) for musculoskeletal pain

British medical journal, 2021
• Oral non-steroidal anti-inflammatory drugs (NSAIDs) can reduce musculoskeletal pain but increase the risk of gastrointestinal (perforation, ulcers, bleeding), cardiovascular (myocardial infarction, heart failure, hypertension), and renal adverse events
G. Machado, Christina Abdel-Shaheed, M. Underwood, R. Day   +3 more
semanticscholar   +1 more source

Effect of NSAIDs on Bone Healing Rates: A Meta-analysis

Journal of the American Academy of Orthopaedic Surgeons, 2019
Introduction: NSAIDs inhibit osteogenesis and may result in delayed union or nonunion. The purpose of this meta-analysis was to determine whether their use leads to delayed union or nonunion.
Benjamin M. Wheatley, Kyle E. Nappo, Daniel L. Christensen, A. Holman, D. Brooks, B. Potter   +5 more
semanticscholar   +1 more source

IFN-induced depression: a role for NSAIDs.

Psychopharmacology bulletin
Interferon-alpha (IFN) is widely used for the treatment of viral illnesses and other chronic diseases, though its usefulness is hampered by a problematic side-effect profile.
G. Asnis, R. De La Garza, S. R. Kohn, J. Reinus, Margaret A. Henderson, Johar Shah   +5 more
semanticscholar   +1 more source

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Pharmacology Mind Maps for Medical Students and Allied Health Professionals, 2019
U Dose reduction or cessation may be considered for all patients taking NSAIDs whose symptoms are under control and are relatively stable. U Some patients may find intermittent use of NSAIDs as effective as continuous use.
Ida Ghlichloo, Valerie A. Gerriets
semanticscholar   +1 more source

NSAID induced gastrointestinal damage and designing GI-sparing NSAIDs

Expert Review of Clinical Pharmacology, 2018
NSAIDs are widely used to treat pain and rheumatic conditions, but they induce adverse events in different body systems, although the major, most frequent events occur in the upper and lower gastrointestinal (GI) tracts.
G. García-Rayado, Mercedes Navarro, Á. Lanas   +2 more
semanticscholar   +1 more source

Prodrugs of Non-steroidal Anti-inflammatory Drugs (NSAIDs): A Long March Towards Synthesis of Safer NSAIDs.

Mini-Reviews in Medical Chemistry, 2018
As a therapeutic group, non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used, prescribed and over the counter (OTC) medications for the treatment of inflammatory diseases, but suffering from several undesired side effects, the ...
Shikha Sehajpal, D. Prasad, R. Singh
semanticscholar   +1 more source

Cardiovascular effects and safety of (non-aspirin) NSAIDs

Nature Reviews Cardiology, 2020
A. Schjerning, P. McGettigan, Gunnar H. Gislason   +2 more
semanticscholar   +1 more source

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Nature, 2001
S. Weggen, J. Eriksen, Pritam Das, S. Sagi, Rong Wang, C. Pietrzik, K. Findlay, Tawnya E. Smith, M. Murphy, T. Bulter, D. Kang, N. Marquez-Sterling, T. Golde, E. Koo   +13 more
semanticscholar   +1 more source

NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies

Journal of Biomolecular Structure and Dynamics, 2018
F. Azam, Nada Hussin Alabdullah, Hadeel Mohammed Ehmedat, Abdullah R Abulifa, Ismail M. Taban, S. Upadhyayula   +5 more
semanticscholar   +1 more source