Results 41 to 50 of about 104,757 (302)

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

Advanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou, Binghua Zhang, Lang Liu, Jie Yang, Yuting Wang, Cheng Lv, He Zhang, Yuchi Wei, Zhanliang Jiang, Zeyu Peng, Daqing Zhao, Xiangyang Leng, Xiangyan Li, Hang Su, Haisi Dong   +14 more
wiley   +1 more source

Mixed Matrix Membrane Tip Extraction Coupled with UPLC–MS/MS for the Monitoring of Nonsteroidal Anti-Inflammatory Drugs in Water Samples

Separations, 2020
An ultra-performance liquid chromatography−tandem mass spectrometry (UPLC−MS/MS) method, in combination with a mixed matrix membrane microextraction method for the quantification of nonsteroidal anti-inflammatory drugs (NSAIDs) in ...
Thipashini Ganesan, Nurul Hazirah Mukhtar, Hong Ngee Lim, Hong Heng See   +3 more
doaj   +1 more source

Characteristics of unintentional ingestion of oral non-steroidal anti-inflammatory drugs and analgesics in preschool children

Arhiv za Higijenu Rada i Toksikologiju, 2021
We characterised accidental ingestion of non-steroidal anti-inflammatory drugs and non-opioid analgesics in children aged 0–5 years between 2009 and 2019 by analysing records of telephone consultations with the Croatian Poison Control Centre (CPCC) and ...
Babić Željka, Kordić Nikolina Benco, Rešić Arnes, Turk Rajka   +3 more
doaj   +1 more source

Factors Associated With Anxiety Symptoms in Older Adults Attending an Outpatient Geriatric Service: A Cross‐Sectional Study

AGING MEDICINE, EarlyView.
An analytical study was carried out by secondary analysis of a database of a study performed between 2010 and 2015 at the Naval Medical Center of Peru (CEMENA). the analysis revealed that depressive symptoms, polypharmacy, slow gait speed, education, and marital status were significant contributors to anxiety in this population.
Gianella Grajeda‐León, Victoria Azurin‐Gonzales, Zulema Mamani‐Condori, Alvaro M. Ñaña‐Cordova, Marina A. Bustamante‐Ordoñez, Fiorella Neyra‐Cordova, José F. Parodi, Fernando M. Runzer Colmenares   +7 more
wiley   +1 more source

A RARE CASE OF MULTIPLE COLONIC ULCERS REVEALED BY HEMATOCHEZIA [PDF]

Romanian Journal of Medical Practice, 2018
Introduction. The colonic pathology associated with the administration of nonsteroidal anti-inflammatory drugs is vast and includes inflammation, ulcerations and sometimes strictures.
Ecaterina Rinja, Madalina Ilie, Vasile Sandru, Irina Diaconu, Oana Plotogea, Andreea Hortopan, Ruxandra Oprita, Alexandru Laurentiu Chiotoroiu, Gabriel Constantinescu   +8 more
doaj   +1 more source

Analysis of the characteristics and management of perforated peptic ulcer from 2011 to 2022: A multicenter and retrospective descriptive study

Annals of Gastroenterological Surgery, EarlyView.
The in‐hospital mortality rate for perforated peptic ulcer in this study was 5.0%, and conservative treatment was safely performed even in elderly patients. As the perforation diameter increased, the rate of gastrectomy tended to rise, and the rate of anastomotic leakage in those patients was high.
Hiromasa Hoshi, Akira Endo, Koji Ito, Tomohiro Akutsu, Hikaru Odera, Hideto Shiraki, Kei Ito, Takeshi Yokoyama, Yasukazu Narita, Taro Masuda, Akira Suekane, Koji Morishita   +11 more
wiley   +1 more source

Pain‐autonomic measures reveal nociceptive sensitization in complex regional pain syndrome

European Journal of Pain, Volume 27, Issue 1, Page 72-85, January 2023., 2023
Abstract Background Allodynia and hyperalgesia are common signs in individuals with complex regional pain syndrome (CRPS), mainly attributed to sensitization of the nociceptive system. Appropriate diagnostic tools for the objective assessment of such hypersensitivities are still lacking, which are essential for the development of mechanism‐based ...
Paulina S. Scheuren, Iara De Schoenmacker, Jan Rosner, Florian Brunner, Armin Curt, Michèle Hubli   +5 more
wiley   +1 more source

New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples [PDF]

Royal Society Open Science, 2018
A magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed ...
Syed Fariq Fathullah Syed Yaacob, Muhammad Afzal Kamboh, Wan Aini Wan Ibrahim, Sharifah Mohamad   +3 more
doaj   +1 more source

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

Aggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai, Mengdie Li, Jinfa Ye, Mingyou Zhang, Jingbin Zhuang, Yuhang Cheng, Hongjin Li, Lang Ke, Xingyuan Wei, Yun Han, Huanhuan Liu, Gang Liu, Chengchao Chu   +12 more
wiley   +1 more source