Results 271 to 280 of about 362,523 (334)
Are two drugs better than one in advanced NSCLC? ABSTRACT Background Randomized studies have demonstrated superior overall survival (OS) of pembrolizumab (pembro), both alone and in combination with chemotherapy (chemo) over chemo alone in patients with programmed cell death ligand‐1 (PD‐L1) ≥ 50% advanced non–small cell lung cancer (NSCLC).
Junipearl Cheng +5 more
wiley +1 more source
Liquid biopsy and tissue biopsy for the detection of EGFR mutations in patients with stage III non-small-cell lung cancer: an observational real-world study. [PDF]
Malapelle U +8 more
europepmc +1 more source
This study explores the current status, utilization, and barriers to circulating tumour DNA (ctDNA) testing in thoracic oncology across Australia and New Zealand. While clinicians recognize the potential of ctDNA for guiding targeted therapy and monitoring disease, real‐world access remains inconsistent due to funding, availability, and infrastructure ...
Yifei Zhu +4 more
wiley +1 more source
Molecular Pathology of Advanced NSCLC: Biomarkers and Therapeutic Decisions. [PDF]
Winter M +4 more
europepmc +1 more source
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown +7 more
wiley +1 more source
Targeting the Uncommon: A Case Report of Osimertinib Response in Advanced NSCLC Patient with Dual EGFR (E701fs and L702fs) Frameshift Deletions. [PDF]
Wong AKQ +4 more
europepmc +1 more source
Tumour progression shows decrease in PD‐L1 expression in matched metastases/primary uveal melanomas
Abstract Purpose Immune checkpoint inhibitors (ICI) have revolutionised the treatment of several malignancies. However, the results of ICI therapy remain unsatisfactory in metastatic uveal melanoma (UM). We analysed the expression of PD1, PD‐L1, T‐cell and macrophage markers in a set of matched primary and metastatic UM in an attempt to better ...
Maria Chiara Gelmi +5 more
wiley +1 more source

