Results 291 to 300 of about 362,523 (334)

KAT2A Deficiency Suppresses Lung Cancer Progression by Downregulating MYC Through Decreasing MYC Succinylation

open access: yesCancer Science, EarlyView.
ABSTRACT Succinylation has been shown to promote lung cancer development, but its mechanism remains incompletely understood. KAT2A, a succinyltransferase, acts as an oncogene in multiple cancers, but its role in mediating lung cancer progression is unclear.
Junping Li   +7 more
wiley   +1 more source

The Diagnosis and Treatment of Lung Cancer: Methods, evidence and guidance [PDF]

open access: yes, 2005
Belchamber, C.A.   +1 more
core  

A11 Peptide Enhances Radiosensitivity by Degrading EphA2 in Nasopharyngeal Carcinoma

open access: yesCancer Science, EarlyView.
In EphA2‐high‐expressing nasopharyngeal carcinoma cells, radiation triggers RSK‐dependent phosphorylation of EphA2 at Ser897, which in turn activates AKT and promote radioresistance. The A11 peptide breaks this signaling cascade by degrading EphA2 and blocking its S897 phosphorylation, thereby markedly enhancing radiosensitivity.
Ming Zhang   +5 more
wiley   +1 more source

Lung Cancer Cells Secrete Glutamine to Accumulate Tumor-Associated Macrophages. [PDF]

open access: yesMol Carcinog
Reddy JP   +7 more
europepmc   +1 more source

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