First Report of <i>RET</i> Fusion-Positive Lung Adenocarcinoma With Miliary Intrapulmonary Metastases Responsive to Selpercatinib: A Case Report. [PDF]
Iwanaka S +11 more
europepmc +1 more source
Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn +4 more
wiley +1 more source
Veratramine Inhibits Human Non-Small Cell Lung Cancer Cell Growth by Inhibiting the Hedgehog Signaling Pathway. [PDF]
Lee SW +12 more
europepmc +1 more source
Exome‐wide molecular insights from blood and urine liquid biopsies in genitourinary cancers
Abstract Background Liquid biopsy has emerged as a non‐invasive method for real‐time cancer monitoring especially in genitourinary (GU) oncology. Most current studies utilize a panel‐based molecular profiling ranging from 50–600 genes; however, a comprehensive exome‐wide profiling of real‐world patient samples has been lacking. Methods Over 2000 liquid
Eric Jia +3 more
wiley +1 more source
The efficacy analysis of neoadjuvant chemoimmunotherapy followed by surgery in stage III locally advanced non-small cell lung cancer: a systematic review and meta-analysis. [PDF]
Yang X +9 more
europepmc +1 more source
The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li +10 more
wiley +1 more source
Immunoproteasome components LMP2, PSME1, and PSME2 as novel tissue biomarkers predicting response and survival in neoadjuvant chemoimmunotherapy for resectable NSCLC. [PDF]
Xie R, Zhai K, Yu J, Zhao M.
europepmc +1 more source
CircRNA in non‑small cell lung cancer: Potential biomarkers and therapeutic targets (Review). [PDF]
Wu Z, Zhu Z, Zhao P, Song Y, Ke X.
europepmc +1 more source
Machine learning and WGCNA reveal the PVT1/miR-143-3p/CDK1 ceRNA axis as a key regulator in NSCLC. [PDF]
Safarzadeh A +3 more
europepmc +1 more source
Targeting tumor microenvironment with biomimetic nanovesicles for non-small cell lung cancer gene therapy. [PDF]
Yan Q +9 more
europepmc +1 more source

