Results 141 to 150 of about 7,712 (169)

Lateral root formation is stimulated by common symbiosis genes and NIN in Lotus japonicus

Cathebras C, Sandré A, Ried-Lasi MK, Parniske M.   +3 more
europepmc   +1 more source

Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins [PDF]

Acta Biochimica Et Biophysica Sinica, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health threat since December 2019, and there is still no highly effective drug to control the pandemic. To facilitate drug target identification for drug development, studies on molecular mechanisms, such as SARS-CoV-2 protein interactions, are urgently needed.
Yunxiao Zheng, Sheng-Ce Tao, Guo Shu-Juan   +2 more
exaly   +3 more sources

Selection and evolutionary analysis in the nonstructural protein NSP2 of rotavirus A

Infection, Genetics and Evolution, 2012
Rotavirus A is the leading cause of acute gastroenteritis in infants and young children worldwide. The nonstructural protein 2 (NSP2) plays essential roles in the replication cycle of rotavirus and may play a role in protective immunity against rotavirus disease.
Nicole Donker, Carl D Kirkwood
exaly   +3 more sources

Structural basis for substrate specificity of alphavirus nsP2 proteases [PDF]

Journal of Molecular Graphics and Modelling, 2010
The alphavirus nsP2 protease is essential for correct processing of the alphavirus nonstructural polyprotein (nsP1234) and replication of the viral genome. We have combined molecular dynamics simulations with our structural studies to reveal features of the nsP2 protease catalytic site and S1'-S4 subsites that regulate the specificity of the protease ...
Stanley Watowich, Mark White
exaly   +3 more sources

NSP2 forms viroplasms during Dendrolimus punctatus cypovirus infection

Virology, 2019
Reoviruses are thought to replicate and assemble in special cytoplasmic structures called 'viroplasms'. However, little is known about the viroplasms of the insect reoviruses, the cypoviruses. To investigate the viroplasm of Dendrolimus punctatus cypovirus (DpCPV), all proteins encoded by the 10 genomic segments of DpCPV were expressed in Sf9 cells ...
Xiulian Sun, Jia Hu, Chengfeng Lei
exaly   +3 more sources

Nuclear localization of Sindbis virus nonstructural protein nsP2 [PDF]

Cell Research, 1993
In early infection, approximately 10% of nonstructural protein nsP2 of Sindbis virus was transported into the nuclei of virus-infected BHK-21 cells. Nuclear nsP2 was dominantly associated with nuclear matrix. During the course of infection, increasing amounts of nsP2 accumulated in the nuclear fraction. A prominent accumulation of nuclear nsP2 occurred
Xiaozhong Wang, Mingxiao Ding, Wang Xiaozhong   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Glutathionylation of chikungunya nsP2 protein affects protease activity

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
Chikungunya fever is an emerging disease caused by the chikungunya virus and is now being spread worldwide by the mosquito Aedes albopictus. The infection can cause a persistent severe joint pain and recent reports link high levels of viremia to neuropathologies and fatalities.
Chonticha, Saisawang, Atichat, Kuadkitkan, Duncan R, Smith, Sukathida, Ubol, Albert J, Ketterman   +4 more
openaire   +2 more sources

Nuclear targeting of Semliki Forest virus nsP2

1994
The Semliki Forest virus-specific nonstructural protein nsP2 is transported into the nuclei of both infected and transfected BHK cells. The pentapeptide sequence P 648R RRV is an essential part of the nuclear localization signal (NLS) of nsP2, the middle arginine being the most critical residue for nuclear targeting.
M, Rikkonen, J, Peränen, L, Kääriäinen   +2 more
openaire   +2 more sources

N⋯Nsp2 hydrogen interactions in organic crystals

Journal of Molecular Structure, 1990
Abstract Crystal structures containing RNH 2 /R,R′NH⋯N sp 2 intermolecular contacts have been retrieved from the Cambridge Structural Data Base. In both independent sets, the higheset concentration of hydrogen interactions occurs in the lone pair nitrogen direction.
A.L. Llamas Saiz, C. Foces-Foces
openaire   +1 more source

Research progress in NSP2 of porcine reproductive and respiratory syndrome virus

Virology
Porcine reproductive and respiratory syndrome virus (PRRSV) Nonstructural Protein 2 (NSP2), a multifunctional protein encoded by a highly variable gene, plays pivotal roles in viral pathogenesis. This review synthesizes current progress on NSP2 genetic variations, including mutations, deletions, and interstrain recombination-with emphasis on its ...
Fang Liang, Jiaman Li, Xiaolin Lan, Yaqiong Ye, Gan Li, Feng Li, Chen Lv, Kexin Liu, Zhiyu Yang, Ruyu Sun, Yajie Zheng, Lin Wang, Huawei Li, Ruining Wang, Keshan Zhang, Mengmeng Zhao   +15 more
openaire   +2 more sources