Results 41 to 50 of about 17,130,313 (339)

Transplantation of Hematopoietic Stem Cells Promotes Functional Improvement Associated with NT-3-MEK-1 Activation in Spinal Cord-Transected Rats. [PDF]

Front Cell Neurosci, 2017
Xiong LL, Liu F, Deng SK, Liu J, Dan QQ, Zhang P, Zou Y, Xia QJ, Wang TH.   +8 more
europepmc   +3 more sources

Neurotrophin-3-enhanced nerve regeneration selectively improves recovery of muscle fibers expressing myosin heavy chains 2b [PDF]

, 1997
The purpose of this study was to evaluate the effect of neurotrophin 3 (NT-3) enhanced nerve regeneration on the reinnervation of a target muscle. Muscle fibers can be classified according to their mechanical properties and myosin heavy chain (MHC ...
Airaksinen, Averbuch-Heller, Bar, Bertelli, Braun, Burke, Davis, DiStefano, Eriksson, Ernfors, Fex, Fields, Gillespie, Goldspink, Green, Griesbeck, Henderson, Henderson, Hughes, Isaacson, Izumo, Jansson, Karpati, Kato, Kucera, Kucera, Lefebvre, Lewin, Li, Lindsay, Lohof, Maltin, Oakley, Ozaki, Pellegrino, Peter, Pette, Romanul, Salmons, Schantz, Schiaffino, Schnell, Sterne, Tessarollo, Totosy de Zepetnek, Vejsada, Wang, Wong, Wright   +48 more
core   +2 more sources

Serum Level Changes of Neurotrophin-3 After Performing Diabetic Foot Exercise in Diabetic Neuropathy [PDF]

, 2015
The research aimed to determine the pattern of changes in serum levels of NT-3 in the improvement of diabetic neuropathy, after doing diabetic foot exercise. A true experimental study with randomaized pre – post test control trial. A total of 36 subjects
Pranoto, A. (Agung), Wahyuliati, T. (Tri), Wibowo, S. (Samekto)   +2 more
core   +3 more sources

Dimeric dipeptide mimetics of neurotrophins as molecular tools and potential neuroprotective drugs [PDF]

Exploration of Drug Science
Proteins from the neurotrophin family perform trophic and regulatory functions in the nervous and other body systems. Understanding the mechanisms of neurotrophin action is crucial not only for the evolution of fundamental scientific knowledge but also ...
Tatiana Gudasheva, Polina Povarnina, Vladimir Dorofeev   +2 more
doaj   +1 more source

Expression of Neurotrophin-3 (NT-3) and Anterograde Axonal Transport of Endogenous NT-3 by Retinal Ganglion Cells in Chick Embryos [PDF]

The Journal of Neuroscience, 2000
Anterograde axonal transport of neurotrophins has been demonstrated recently, but to date such transport has only been shown for brain-derived neurotrophic factor and no other endogenous neurotrophin. Endogenous neurotrophin-3 (NT-3) protein is present in the ganglion cell layer of the chicken retina, as well as the superficial layers of the optic ...
C S, von Bartheld, R, Butowt
openaire   +2 more sources

Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury. [PDF]

, 2009
A principal objective of spinal cord injury (SCI) research is the restoration of axonal connectivity to denervated targets. We tested the hypothesis that chemotropic mechanisms would guide regenerating spinal cord axons to appropriate brainstem targets ...
Alto, Laura Taylor, Blesch, Armin, Conner, James M, Havton, Leif A, Hollis, Edmund R, Tuszynski, Mark H   +5 more
core   +2 more sources

Expression of Neurotrophins and Their Receptors Tropomyosin-related kinases (Trk) under Tension-stress during Distraction Osteogenesis [PDF]

, 2006
The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation.
Aiga, Ayako, Asaumi, Koji, Kadota, Hiroaki, Lee, You Jin, Mitani, Shigeru, Ozaki, Toshifumi, Takigawa, Masaharu   +6 more
core   +1 more source

Neurotrophins‐3 plays a vital role in anti‐apoptosis associated with NGF and BDNF regulation in neonatal rats with hypoxic‐ischemic brain injury

Ibrain, 2020
Objective To explore the role of Neurotropfin‐3 (NT‐3) in hypoxic‐ischemic encephalopathy (HIE) and determine its relative molecular mechanism. Methods The expression of NT‐3 was determined by qRT‐PCR in the cortex after HIE and immunofluorescence ...
Qiu‐Xia Xiao, Jun‐Jie Chen, Chang‐Le Fang, Zhang‐Yu Su, Ting‐Hua Wang   +4 more
doaj   +1 more source

The effects of controlled release of neurotrophin-3 from PCLA scaffolds on the survival and neuronal differentiation of transplanted neural stem cells in a rat spinal cord injury model. [PDF]

PLoS ONE, 2014
Neural stem cells (NSCs) have emerged as a potential source for cell replacement therapy following spinal cord injury (SCI). However, poor survival and low neuronal differentiation remain major obstacles to the use of NSCs. Biomaterials with neurotrophic
Shuo Tang, Xiang Liao, Bo Shi, Yanzhen Qu, Zeyu Huang, Qiang Lin, Xiaodong Guo, Fuxing Pei   +7 more
doaj   +1 more source

Dose-dependent differential effect of neurotrophic factors on in vitro and in iivo regeneration of motor and sensory neurons [PDF]

, 2016
Although peripheral axons can regenerate after nerve transection and repair, functional recovery is usually poor due to inaccurate reinnervation. Neurotrophic factors promote directional guidance to regenerating axons and their selective application may ...
Del Valle, Jaume, González Pérez, Francisco J., Navarro, Xavier, Santos, Daniel   +3 more
core   +5 more sources