Normal versus pathological cardiac fibroblast-derived extracellular matrix differentially modulates cardiosphere-derived cell paracrine properties and commitment [PDF]
, 2017 Human resident cardiac progenitor cells (CPCs) isolated as cardiosphere-derived cells (CDCs) are under clinical evaluation as a therapeutic product for cardiac regenerative medicine.
Angelini, Francesco +11 more
core +3 more sources
Functional Diversity of Neurotrophin Actions on the Oculomotor System [PDF]
, 2016 Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance of appropriate adult neuronal circuits and phenotypes.
Benítez Temiño, Beatriz +5 more
core +1 more source
Stem Cell Research & Therapy, 2021 Background Efficient and stable delivery of neurotrophic factors (NTFs) is crucial to provide suitable microenvironment for peripheral nerve regeneration.
Zheng Yang +7 more
doaj +1 more source
A peptidomimetic of NT-3 acts as a TrkC antagonist [PDF]
Peptides, 2009 Neurotrophins are a family of growth factors that regulate the peripheral and central nervous system. We designed and tested a mini-library of small molecules peptidomimetics based on beta-turns of the neurotrophin growth factor polypeptides NT-3, which is the natural ligand for TrkC receptors.
Fouad, Brahimi +6 more
openaire +2 more sources
The effect of cigarette price increase on the cigarette consumption in Taiwan: evidence from the National Health Interview Surveys on cigarette consumption [PDF]
, 2004 BACKGROUND: This study uses cigarette price elasticity to evaluate the effect of a new excise tax increase on cigarette consumption and to investigate responses from various types of smokers.
Chun-Yuan Ye +20 more
core +2 more sources
eLife, 2018 Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10) contusive ...
Ying Wang +17 more
doaj +1 more source
Controlled release of neurotrophin-3 and platelet-derived growth factor from fibrin scaffolds containing neural progenitor cells enhances survival and differentiation into neurons in a subacute model of SCI [PDF]
, 2010 A consistent problem with stem/neural progenitor cell transplantation following spinal cord injury (SCI) is poor cell survival and uncontrolled differentiation following transplantation.
Johnson, Philip J +3 more
core +2 more sources
Stem Cells Translational Medicine, 2021 Acute myocardial infarction (MI) resulting from coronary ischemia is a major cause of disability and death worldwide. Transplantation of human embryonic stem cell (hESC)‐derived cardiovascular progenitor cells (hCVPCs) promotes the healing of infarcted ...
Wei Bi +10 more
doaj +1 more source
Neural progenitor cell implants modulate vascular endothelial growth factor and brain-derived neurotrophic factor expression in rat axotomized neurons [PDF]
, 2003 Axotomy of central neurons leads to functional and structural alterations which largely revert when neural progenitor cells (NPCs) are implanted in the lesion site. The new microenvironment created by NPCs in the host tissue might modulate in the damaged
B. Faltings +4 more
core +3 more sources
Apmerengentyele—Our Systems, Our Children, Our Safety, Our Wellbeing
GenealogyWestern systems of child protection cannot protect First Nations children. Australia’s current child protection systems were born from a legislated and explicit intention of destroying the culture, language and identity of First Nations children, with ...
William Tilmouth +3 more
doaj +1 more source