Results 61 to 70 of about 17,130,313 (339)

Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease

Antioxidants, 2021
Background. Salivary α-synuclein (aSyn) and its nitrated form, or 3-nitrotyrosine-α-synuclein (3-NT-αSyn), hold promise as biomarkers for idiopathic Parkinson’s disease (IPD).
Emilio Fernández-Espejo, Fernando Rodríguez de Fonseca, Juan Suárez, Eduardo Tolosa, Dolores Vilas, Iban Aldecoa, Joan Berenguer, Fátima Damas-Hermoso   +7 more
doaj   +1 more source

Cytokine expression in human dermal fibroblasts stimulated with eosinophil cationic protein measured by protein array [PDF]

, 2013
[Background] : Eosinophil cationic protein (ECP) was reported previously to be involved in allergic inflammation with cytotoxic activity. On the other hand, recent studies showed that ECP did not induce cell death but inhibited the growth of cancer ...
Maeda, Hiroshi, Meguro, Michio, Otani, Takayuki, Sato, Takamaro, Seno, Masaharu, Soga, Yoshihiko, Tada, Joji, Takashiba, Shogo, Yamaguchi, Tomoko   +8 more
core   +1 more source

Effect of Neurotrophin-3 Genetically Modified Olfactory Ensheathing Cells Transplantation on Spinal Cord Injury

Cell Transplantation, 2010
Transplantation of olfactory ensheathing cells (OECs) has emerged as a very promising therapy for spinal cord injury (SCI). Also, local delivery of NT-3 can counteract pathological events and induce a regenerative response after SCI.
Yu-Hai Ma, Yong Zhang, Li Cao, Jia-Can Su, Zhi-Wei Wang, A-Bing Xu, Shao-Cheng Zhang   +6 more
doaj   +1 more source

Neurotrophin-3 Promotes Cell Death Induced in Cerebral Ischemia, Oxygen-Glucose Deprivation, and Oxidative Stress: Possible Involvement of Oxygen Free Radicals

Neurobiology of Disease, 2002
To explore the role of neurotrophin-3 (NT-3) during cerebral ischemia, NT-3-deficient brains were subjected to transient focal ischemia. Conditional mutant brains produced undetectable amounts of NT-3 mRNA, whereas the expression of the neurotrophin ...
Brian Bates, Lorenz Hirt, Sunu S. Thomas, Schahram Akbarian, Dean Le, Sepideh Amin-Hanjani, Michael Whalen, Rudolf Jaenisch, Michael A. Moskowitz   +8 more
doaj   +1 more source

Neurotrophin-3 accelerates reendothelialization through inducing EPC mobilization and homing

Open Life Sciences, 2020
Rapid endothelialization is an effective way to treat intimal hyperplasia after intravascular stent implantation. Blood vessels and nerves coordinate with each other in function, while neurotrophin-3 (NT-3) is an important class of nerve growth factors ...
Chen Yan, Cao Jian, Peng Weixia, Chen Wen   +3 more
doaj   +1 more source

Neurotrophin-3 Promotes the Neuronal Differentiation of BMSCs and Improves Cognitive Function in a Rat Model of Alzheimer's Disease

Frontiers in Cellular Neuroscience, 2021
Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) has the potential to be developed into an effective treatment for neurodegenerative diseases such as Alzheimer's disease (AD).
Zhongrui Yan, Zhongrui Yan, Xianjing Shi, Hui Wang, Cuiping Si, Qian Liu, Yifeng Du, Yifeng Du   +7 more
doaj   +1 more source

Reductive modification of genetically encoded 3-nitrotyrosine sites in alpha synuclein expressed in E.coli

Redox Biology, 2019
Tyrosine nitration is a post-translational protein modification relevant to various pathophysiological processes. Chemical nitration procedures have been used to generate and study nitrated proteins, but these methods regularly lead to modifications at ...
Hanne R. Gerding, Christiaan Karreman, Andreas Daiber, Johannes Delp, Daniel Hammler, Martin Mex, Stefan Schildknecht, Marcel Leist   +7 more
doaj   +1 more source

N-Terminal Pro-brain Natriuretic Peptide Is Associated With Hemorrhagic Transformation and Poor Outcomes in Patients With Stroke Treated With Intravenous Thrombolysis

Frontiers in Molecular Neuroscience, 2021
Background: N-terminal pro-brain natriuretic peptide (NT-proBNP) levels are a promising biomarker for predicting stroke outcomes; however, their prognostic validity is not well-understood in patients who have undergone intravenous thrombolysis.
Ke-Jia Zhang, Ke-Jia Zhang, Hang Jin, Hang Jin, Rui Xu, Rui Xu, Peng Zhang, Peng Zhang, Zhen-Ni Guo, Zhen-Ni Guo, Yi Yang, Yi Yang   +11 more
doaj   +1 more source

Herpes simplex virus type 1-mediated transfer of neurotrophin-3 stimulates survival of chicken auditory sensory neurons [PDF]

, 2013
El pdf del artículo es la versión pre-print.-- et al.Neurotrophin-3 (NT-3) is one of the most potent stimulators for survival of auditory sensory neurons.
Alonso, María Teresa, Carnicero, Estela, Schimmang, Thomas   +2 more
core   +2 more sources

Neurotrophins and neurotrophin receptors in proliferative diabetic retinopathy. [PDF]

PLoS ONE, 2013
Neurotrophins (NTs) are emerging as important mediators of angiogenesis and fibrosis. We investigated the expression of the NTs nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) and ...
Ahmed M Abu El-Asrar, Ghulam Mohammad, Gert De Hertogh, Mohd Imtiaz Nawaz, Kathleen Van Den Eynde, Mohammad Mairaj Siddiquei, Sofie Struyf, Ghislain Opdenakker, Karel Geboes   +8 more
doaj   +1 more source