Results 171 to 180 of about 70,470 (286)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Prognostic Value of NT-proBNP in Patients Treated With Allogeneic Stem Cell Transplantation. [PDF]

JACC Adv
Polomski EAS, von dem Borne PA, Veelken H, Heemelaar JC, Jukema JW, Antoni ML.   +5 more
europepmc   +1 more source

Phenotyping of Fontan‐Associated Renal Physiology and Disease

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
In patients with a Fontan circulation, both kidney function and glomerular injury progressively decline with age, with a stronger decline than in healthy individuals. Additionally, intrarenal haemodynamics in patients with a Fontan circulation demonstrate decreased venous and arterial compliance, evident through elevated venous impedance and renal ...
Gaston van Hassel, Jozine M. ter Maaten, Iris E. Beldhuis, Eryn T. Liem, Bastiaan Zwart, Stephan J. L. Bakker, Rolf M. F. Berger, Joost P. van Melle   +7 more
wiley   +1 more source

Anatomical Predictors of Optimal Cryoballoon Size Selection: A Prospective Comparison of 28 mm Versus 31 mm Size‐Adjustable Balloon Modes

Journal of Arrhythmia, Volume 42, Issue 2, April 2026.
The 31 mm POLARx FIT cryoballoon achieves significantly higher complete pulmonary vein occlusion rates than the 28 mm mode, particularly in superior veins. Larger PV diameter and higher ovality index independently predict incomplete occlusion, supporting pre‐procedural CT‐based anatomical assessment for individualized balloon size selection.
Reisuke Yoshizawa, Takeshi Sasaki, Harutomo Numazaki, Keisuke Kaminaga, Kotaro Mori, Satoru Taguchi, Hiroki Sasaki, Takashi Urushikubo, Kyohei Nagata, Yohei Sawa, Shingen Owada, Fumiaki Takahashi, Yoshihiro Morino   +12 more
wiley   +1 more source

Association of NT-proBNP and sST2 with Diastolic Dysfunction in Cirrhotic Patients and Its Therapeutic Implications. [PDF]

Int J Mol Sci
Chiorescu RM, Ruda A, Chira R, Nagy G, Bințințan A, Chiorescu Ș, Mocan M.   +6 more
europepmc   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

NT-proBNP With Postoperative Complications and 2-Year Mortality Among Hip Fracture Patients: An Observational Cohort Study. [PDF]

Orthop Surg
Lin X, Jiang Y, Wang Y, Tan S, Cui X, Luo Y, Lyu H, Zhang L, Tang P.   +8 more
europepmc   +1 more source

Comparative effectiveness of pharmacotherapy for heart failure with preserved ejection fraction: A systematic review and network meta‐analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3137-3145, April 2026.
Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting adiposity is central to HFpEF pathogenesis. We conducted an updated network meta‐analysis to compare the efficacy of emerging and established HFpEF therapies ...
Szu‐Han Chen, Yu‐Wen Tseng, Chi‐Jung Huang, Shu‐Mei Yang, Marat Fudim, Shao‐Yuan Chuang, Shih‐Hsien Sung, Hao‐Min Cheng   +7 more
wiley   +1 more source

Long-Term Outcomes in Hemodialysis Patients According to Combined NT-proBNP and Galectin-3 Biomarker Profiles. [PDF]

J Clin Med
Stefan AE, Covic A, Covic MA, Dodi G, Apetrii M, Onofriescu M, Hogas S, Iliescu S, Voroneanu L.   +8 more
europepmc   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3254-3263, April 2026.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone, Erik Moedt, Hiddo J. L. Heerspink, Michael J. Davies, Manon Girard, David Z. I. Cherney, Marcel H. A. Muskiet   +6 more
wiley   +1 more source