Naringin Regulates Microglia BV-2 Activation and Inflammation via the JAK/STAT3 Pathway. [PDF]
Evid Based Complement Alternat Med, 2022 Objective. Microglial BV‐2 cells are activated in the brain following insomnia. Naringin (NAR) is a polymethoxylated flavonoid that is also commonly found in citrus fruits and is known for its antioxidant potential. However, the effect of NAR on microglial cells has rarely been studied in the brain of an organism after insomnia.
Li L +6 more
europepmc +3 more sources
Alleviating effect of Lactobacillus pentosus CQZC01 probiotic strain on antibiotic-induced diarrhea in mice [PDF]
Acta Poloniae PharmaceuticaThis experiment used mice as the experimental subjects to study the alleviating effect of Lactobacillus pentosus CQZC01 (LPCQZC01) on antibiotic-induced diarrhea in mice. After adaptive feeding for seven days, Kunming (KM) mice were randomly divided into
YANQING LIU +8 more
doaj +3 more sources
Interleukin-6 Levels in the Cervicovaginal Fluid of Pregnant Women and Its Predictive Value in Preterm Delivery [PDF]
Bagcilar Medical Bulletin, 2020 Objective:The aim of this study was to determine interleukin (IL)-6 levels in the cervicovaginal fluid of pregnant women and its value in predicting preterm delivery.Method:One hundred and eleven pregnant women were retrospectively included in the study.
Pelin Ergenekon
doaj +2 more sources
Journal of Pediatric Research, 2019 Aim:Cryopyrin-associated Periodic Syndromes (CAPS) are a subgroup of the Periodic fever syndromes, caused by mutations in the NLRP3 gene. NLRP3 gene mutations can cause three clinically different phenotypes.
Berk Özyılmaz, Taha Reşid Özdemir
doaj +2 more sources
Senescent Cells Involved in Deterioration of Bone Microstructure by High-Frequency Parathyroid Hormone 1-34 Administration and Bone Loss. [PDF]
Aging CellSenescent osteoblasts induced by PTH contribute to cortical bone loss in aged mice. Senolytic co‐treatment reduces senescence and prevents bone loss after PTH withdrawal, enhancing the durability of osteoporosis therapy. ABSTRACT Osteoporosis is characterized by reduced bone mass and structural deterioration, leading to increased fracture risk ...
Bun M +12 more
europepmc +2 more sources
A Mendelian Randomization Study and Experimental Validation Investigating the Potential Relationship Among Interleukin-6 Receptor Subunit Beta, Obesity, and Alzheimer's Disease. [PDF]
Brain BehavThis study employs Mendelian randomization (MR) aimed at systematically evaluating the relationship among interleukin‐6 receptor subunit beta, obesity, and Alzheimer's disease (AD). ABSTRACT Objective This study employs Mendelian randomization (MR) aimed at systematically evaluating the relationship among interleukin‐6 receptor subunit beta, obesity ...
Liu Y, Song N, Wang Q, Cui P, Min D.
europepmc +2 more sources
The Protective Effects of Dendrobine on LPS-Induced Neuroinflammation and Related Mechanisms Based on Microglial M1/M2 Polarization. [PDF]
NutrientsCui J +6 more
europepmc +2 more sources
Human umbilical cord mesenchymal stem cells improve disease characterization of Sjogren's syndrome in NOD mice through regulation of gut microbiota and Treg/Th17 cellular immunity. [PDF]
Immun Inflamm DisThe intervention of umbilical cord (UC)‐mesenchymal stem cells (MSCs) and UC‐MSC and derived exosomes improved intestinal homeostasis in NOD mice by increasing microbiota diversity and richness. Additionally, differential microbiota was significantly associated with Treg/Th17 cytokine levels.
Zou Y +8 more
europepmc +2 more sources
Acupuncture Inhibits Morphine Induced‐Immune Suppress via Antioxidant System
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Objectives. A powerful analgesic called Morphine causes addiction behaviors and immune suppression as a potential oxidative stressor. Acupuncture showed to inhibit oxidative stress‐induced hepatic damage, regulate reactive oxygen species, and attenuate morphine addiction behaviors.
Rong Jie Zhao +11 more
wiley +1 more source
Clinical &Experimental Immunology, Volume 205, Issue 3, Page 288-305, September 2021., 2021 Lymphadenopathies can be part of the clinical spectrum of several primary immunodeficiencies, diseases with immune dysregulation, and autoinflammatory disorders, as the clinical expression of benign polyclonal lymphoproliferation, granulomatous disease, or lymphoid malignancy.
Giorgio Costagliola, Rita Consolini
wiley +1 more source