Results 21 to 30 of about 303 (119)

Review article: impact of cigarette smoking on intestinal inflammation—direct and indirect mechanisms

Alimentary Pharmacology &Therapeutics, Volume 51, Issue 12, Page 1268-1285, June 2020., 2020
Summary Background The inflammatory bowel diseases, Crohn's disease and ulcerative colitis are related multifactorial diseases. Their pathogenesis is influenced by each individual's immune system, the environmental factors within exposome and genetic predisposition.
Stamatia Papoutsopoulou, Jack Satsangi, Barry J. Campbell, Chris S. Probert   +3 more
wiley   +1 more source

Cytotoxic and Immunomodulatory Effects of <i>Phormidesmis molle</i> Extract on Human Cells In Vitro. [PDF]

Int J Mol Sci
Teneva I, Bardarov K, Batsalova T, Moten D, Dzhambazov B.   +4 more
europepmc   +2 more sources

Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice [PDF]

, 2003
IL-7 is a critical component of thymopoiesis in animals and has recently been shown to play an important role in T cell ho-meostasis. Although there is increasing interest in the use of IL-7 for the treatment of lymphopenia caused by the HIV type 1 ...
Hanley, Mary Beth, Joseph M. Mccune, Eric Wieder, Napolitano, Laura A, McCune, Joseph M, Laura A. Napolitano, Wieder, Eric, Mary Beth Hanley, Cheryl A. Stoddart, Stoddart, Cheryl A   +9 more
core   +1 more source

I nterleukin‐15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab

Immunology, 2012
Summary Interleukin‐15 ( IL ‐15) is a pro‐inflammatory cytokine thought to contribute to the inflammation in inflammatory bowel diseases ( IBD ). The specific receptor chain IL ‐15
Clémentine, Perrier, Ingrid, Arijs, Dominiek, Staelens, Christine, Breynaert, Isabelle, Cleynen, Kris, Covens, Marc, Ferrante, Gert, Van Assche, Séverine, Vermeire, Gert, de Hertogh, Frans, Schuit, Paul, Rutgeerts, Jan L, Ceuppens   +12 more
openaire   +3 more sources

Interleukin‐7 supports survival of T‐cell receptor‐β‐expressing CD4⁻ CD8⁻ double‐negative thymocytes

Immunology, 2013
SummaryAmong the milestones that occur during T‐cell development in the thymus is the expression of T‐cell receptor‐β (TCR‐β) and the formation of the pre‐TCR complex. Signals emanating from the pre‐TCR trigger survival, proliferation and differentiation of T‐cell precursors.
Juan, Xiong, Brooks L, Parker, Stacy L, Dalheimer, Thomas M, Yankee   +3 more
openaire   +3 more sources

Why Does Pnemococcus Kill?

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 10, Issue C, Page 49C-60C, 1999., 1999
Acute lower respiratory tract infections remain the most common cause of death due to infection worldwide, and Streptococcus pneumoniae is responsible for approximately 30% of all cases of community‐acquired pneumonia. While many virulence factors have been associated with fatal pneumococcal pneumonia.
Yves Bergeron, Michel G Bergeron
wiley   +1 more source

Measurement of Amniotic Fluid Interleukin‐6 Using Commercial Kits

Infectious Diseases in Obstetrics and Gynecology, Volume 5, Issue 3, Page 222-225, 1997., 1997
Objective: The association between increased amniotic fluid interleukin‐6 (IL‐6) concentrations and preterm labor has received increasing attention. Several research groups have evaluated this association using commercial IL‐6 kits, which principally use the sandwich‐enzyme‐immunoassay method, and were originally created to measure IL‐6 in plasma ...
Tsunenobu Tamura, William W. Andrews, Kelley E. Johnston, G. Philamon Hemstreet, Robert L. Goldenberg   +4 more
wiley   +1 more source

Successful Outcome With Second Hematopoietic Stem Cell Transplantation in A Patient With IL-10R Deficiency

, 2016
nterleukin-10 (IL-10) and IL-10 receptor (IL-10R) deficiencies, which are caused by loss of function mutations in the related genes, are primary immunodeficiencies that result in severe dysregulation of the immune system.1, 2 Patients usually present ...
Kuskonmaz, Baris, Erman, B, Aydemir, Yusuf, Ayvaz, Deniz, Uckan Cetinkaya, Duygu, Tavil, Betül, Ozen, Hasan, Tezcan, Ilhan, Cetinkaya, D. U., ÇAĞDAŞ AYVAZ, DENİZ NAZİRE, Erman, B., Ayvaz, DENİZ NAZİRE, Aydemir, Y., Tavil, B., KUŞKONMAZ, BÜLENT BARIŞ, Tezcan, I., ERMAN, BARAN   +16 more
core   +1 more source

Tissue eosinophilia induced by recombinant human interleukin‐5 in the hamster cheek pouch membrane

Mediators of Inflammation, Volume 4, Issue 5, Page 331-338, 1995., 1995
Interleukin‐5 (IL‐5) is a cytokine that preferentially effects the development and function of eosinophils, and is considered important in the pathophysiology of allergic inflammation. In this study, we evaluated the ability of recombinant human IL‐5 (rHu IL‐5) to promote tissue eosinophilia and the importance of this eosinophilia to pathological ...
M. Minnicozzi, W. N. Durán, D. Kim, G. J. Gleich, J. Wagner, R. W. Egan   +5 more
wiley   +1 more source

Interferons: Antiangiogenesis Agents (A Reasonable Theory)

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 3, Issue B, Page 128-132, 1992., 1992
Antiviral and immunomodulatory effects of interferons (IFNs) are well‐known. This communication lists arguments for explicit antiangiogenetic effects exerted by interferons. There is strong likelihood that IFNs α, β and γ inhibit the int family of genes whose gene product proteins are the acidic and basic fibroblast growth factors. Some of these growth
Joseph G Sinkovics
wiley   +1 more source