EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer. [PDF]
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Lv C +8 more
europepmc +2 more sources
Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**
Broad screening of the substrate specificity of SIRT7 revealed a strong preference for the cleavage of long‐chain acyllysine modifications. The activity was substantially increased in the presence of oligonucleotides or nucleosome particles. Finally, random nonstandard peptide integrated discovery (RaPID) delivered a cyclopeptide with potency in the ...
Julie E. Bolding +10 more
wiley +2 more sources
Four new species of Tremella (Tremellales, Basidiomycota) based on morphology and DNA sequence data [PDF]
In the present study, a total of 33 Tremella specimens in China were collected and examined using molecular phylogenetic analysis based on a combined sequence dataset of the nuc rDNA internal transcribed spacer (ITS) region and nuc 28S rDNA D1/D2 domain ...
Ying Zhao, Xin-zhan Liu, Feng-yan Bai
doaj +3 more sources
Phylogenetic analyses inferred from the nuc rDNA ITS1-5.8S-ITS2 (ITS) data set and the combined 2-locus data set [5.8S + nuc 28S rDNA (nLSU)] of taxa of Trechisporales around the world show that Sistotremastrum family forms a monophyletic lineage within ...
Zhan-Bo Liu +8 more
doaj +1 more source
Asproinocybe and Tricholosporum are not well known, and their placement at the family level remains undetermined. In this study, we conducted molecular phylogenetic analyses based on nuc rDNA internal transcribed spacer region (ITS) and nuc 28S rDNA ...
Guang-Fu Mou, Tolgor Bau
doaj +1 more source
Two new species of Phylloporus (Fungi, Boletales) from tropical Quercus forests in eastern Mexico [PDF]
We present a proposal of two new species of Phylloporus discovered in tropical oak forests from central Veracruz, Mexico. Both species were distinguished based on macro and micro-morphologic features and supported with a molecular phylogenetic analysis ...
Leticia Montoya +2 more
doaj +3 more sources
Two new species of Trichoglossum (Geoglossaceae, Ascomycota) from south Mexico [PDF]
Two new species of Trichoglossum are described from south Mexico based on morphological and molecular evidence. Trichoglossum caespitosum is characterized by the caespitose ascomata, rough and coiled paraphyses and the ascospores with 9–11 septa ...
Javier Isaac de la Fuente +7 more
doaj +3 more sources
Of Commensals and Opportunists: Genomics of Coagulase-Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult. [PDF]
The genomes of coagulase‐negative staphylococci (CoNS) isolated during sequential ear and eye infections in a healthy adult are analyzed. We highlight the identification of a community‐acquired S. capitis subsp. urealyticus ST1 lineage carrying a mosaic SCCmec IV element, linking common skin commensals to multidrug‐resistant strains associated with ...
Lean SS +6 more
europepmc +2 more sources
Lyomyces denudatus, a new species with a disjunct distribution
We describe a new corticioid species Lyomyces denudatus based on morphological and molecular data (nuc rDNA ITS). It occurs both in the extreme south of South America and New Zealand. Our phylogenetic analyses place it near L.
Ilya Viner, Otto Miettinen
doaj +1 more source
Two new species of Lactifluus (Fungi, Russulales) from tropical Quercus forest in eastern Mexico [PDF]
Two new species of Lactifluus subgenus Lactifluus were discovered during a three-year monitoring of the ectomycorrhizal fungi in a tropical oak forest from central Veracruz, Mexico. Systematic sampling of basidiomes allowed recording of the morphological
Leticia Montoya +3 more
doaj +3 more sources

