Results 121 to 130 of about 3,482,856 (317)

Design of an Organic Simplified Nuclear Reactor [PDF]

open access: yes, 2018
Numerous advanced reactor concepts have been proposed to replace light water reactors ever since their establishment as the dominant technology for nuclear energy production.
Forrest, Eric, Shirvan, Koroush
core   +1 more source

NUCLEAR STRUCTURE VERSUS NUCLEAR PATTERN [PDF]

open access: yesBlood, 1948
Abstract 1. Lymphoid cells from rat and human fetal livers and adult rat lymph nodes were studied by means of various cytologic, cytochemical and optical technics. 2. Freshly dried smears preserve cytoplasmic detail with an extraordinary degree of accuracy. 3. Mitochondria, both numerous and pleomorphic, are
openaire   +2 more sources

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Análisis de la fenomenología del ruido neutrónico en un reactor nuclear. Estudio de los armónicos en señales de potencia mediante los códigos acoplados TRACE y PARCSv3.2 [PDF]

open access: yes, 2019
[ES] El objetivo del presente trabajo ha sido la mejora en la comprensión sobre la fenomenología del ruido neutrónico presente en reactores de agua ligera. Que en el caso de los diseños KWU, además de desconocerse su origen, puede provocar oscilaciones
Redondo, Elena   +6 more
core  

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The influence of leadership on safety culture [PDF]

open access: yesEkonomija: teorija i praksa, 2017
This paper defines what safety culture, safety climate, and safety leadership are. Furthermore, it addresses the influence of leadership as well as quantifiable elements of the influence of leadership on the culture of safety, including communication ...
Lalović Pavle
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Safety and security [PDF]

open access: yes, 2012
This paper is the sixth in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.The document covers accident risk in plants (including a historical review of accidents), threats from design ...
AMEC NNC Limited   +2 more
core  

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