Results 81 to 90 of about 6,280 (278)
Atomic Bomb Survivors’ Views on the Possibility of the Abolition of Nuclear Weapons [PDF]
, 2017 The world’s first atomic bombs exploded over the citizens of Hiroshima and Nagasaki more than seventy years ago. Since then, the survivors (hibakusha) have campaigned for the abolition of nuclear weapons.
van der DOES, Luli +3 more
core +1 more source
Advanced Science, EarlyView.We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha +13 more
wiley +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Application of JC1 for non-toxic isolation of cells with MDR transporter activity by flow cytometry.
PLoS ONE, 2017 The DNA intercalating dye Hoechst 33342 or its close analog DCV are actively removed from cells by the multidrug resistance transporter ABCG2, a protein overexpressed in metastatic cells and somatic stem cells.
J Mario Wolosin +2 more
doaj +1 more source
The Truth About Nuclear Power: Japanese Nuclear Engineer Calls for Abolition
Asia-Pacific Journal, 2011 Koide Hiroaki began his career as a nuclear engineer forty years ago drawn to the promise of nuclear power. Quickly, however, he recognized the flaws in Japan's nuclear power program and emerged as among the best informed of Japan's nuclear power critic.
Satoko Oka Norimatsu +2 more
openaire +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
Nuclear Arms Control and Disarmament Policy Under the Kishida Administration
Journal for Peace and Nuclear DisarmamentThis study examines the Kishida administration’s nuclear arms control and disarmament policies through the lens of Japan’s dual responsibilities: the normative responsibility to pursue a world without nuclear weapons and the strategic responsibility to ...
Hirofumi Tosaki
doaj +1 more source
Advanced Science, EarlyView.This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang +12 more
wiley +1 more source