Results 61 to 70 of about 1,457,964 (285)
Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy +7 more
wiley +1 more source
Introduction: Reducing the Risk of Nuclear Weapons Use in Northeast Asia
This paper summarises the joint collaborative project between the Nautilus Institute, the Research Center for Nuclear Weapon Abolition, Nagasaki University (RECNA), the Asia Pacific Leadership Network for Nuclear Non-Proliferation and Disarmament (APLN ...
Shatabhisha Shetty
doaj +1 more source
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Macmillan's Role in Resolving International Crises (1958-1962) (Selected Models) [PDF]
Several international crises erupted in which British Prime Minister Harold Macmillan played a distinguished role, especially the second Berlin crisis 1958-1960, as he had an important role in easing tensions through his visit to Moscow Especially after ...
Hussein Hammad Abid +1 more
doaj +1 more source
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu +10 more
wiley +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Nuclear Weapons Don’t Belong on Our Planet
In January 2024, the newly appointed Executive Director of the International Campaign to Abolish Nuclear Weapons (ICAN), Melissa Parke, visited Hiroshima and Nagasaki for the first time, where she met with atomic bomb survivors (hibakusha), officials ...
Melissa Parke
doaj +1 more source
The Treaty is Out of the Bottle: The Power and Logic of Nuclear Disarmament
The nuclear genie is out of the bottle, manifesting as nuclear proliferation. Efforts to contain it have generated another genie whose agenda is to establish a verifiable nuclear disarmament regime.
Merav Datan, Jürgen Scheffran
doaj +1 more source
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source

