Results 51 to 60 of about 1,457,964 (285)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

End of the INF Treaty: Are We Entering a New Cold War Era?

open access: yesGazi Akademik Bakış, 2021
This article analyzes possible consequences of the abolition of the Intermediate-Range Nuclear Forces (INF) Treaty, signed between the US and the USSR in 1987 and banning developing, testing and deploying intermediate-range missiles.
Şafak OĞUZ, Mehmet Seyfettin EROL
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

"Securing our survival (SOS)": non-state actors and the campaign for a nuclear weapons convention through the prism of securitisation theory [PDF]

open access: yesBrazilian Political Science Review, 2013
This article analyses the security practices of the anti-nuclear movement in the post-Cold War period through the prism of securitisation theory. By exploring Buzan and Wæver's conceptual developments on macrosecuritisations, the practices involved in ...
Renata H. Dalaqua
doaj  

Trump and the Interregnum of American Nuclear Hegemony

open access: yesJournal for Peace and Nuclear Disarmament, 2018
Nuclear weapons are the ultimate power capacity of states. They make it possible to exterminate whole states, cities and peoples almost instantaneously. Because they are militarily unusable in almost any conceivable context, their main (but not only) use
Peter Hayes
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Vol.6 No.2 [PDF]

open access: yes
RECNA Newsletter, 6(2), pp.1-4 ...
Research Center for Nuclear Weapons Abolition (RECNA)
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

What Should the International Non-Proliferation Regime Look Like Today and Over the Next 10 to 20 Years?

open access: yesJournal for Peace and Nuclear Disarmament
Frustration over the lack of progress in nuclear disarmament under the Nuclear Non-Proliferation Treaty (NPT) led to the creation of the Treaty on the Prohibition of Nuclear Weapons (TPNW). On the other hand, there is criticism that the TPNW has fostered
Andreas Persbo, Kseniia Pirnavskaia
doaj   +1 more source

Nuclear Regulatory Commission Report NUREG-0084

open access: yes, 1977
The proposed project: Pursuant to the Atomic Energy Act, as amended, the U.S. Nuclear Regulatory Commission's regulations in Title 10, Code of Federal Regulations, an application with an accompanying Environmental Report, was filed by Northeast Utilities
U.S. Nuclear Regulatory Commission. Office of Nuclear Reactor Regulation.
core  

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