Results 31 to 40 of about 78,857 (309)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

On the stability of AdS backgrounds with λ-deformed factors

Journal of High Energy Physics, 2021
We investigate the stability of the non-supersymmetric solutions of type-IIB supergravity having an unwarped AdS factor and λ-deformed subspaces found in [26]. Among the plethora of solutions we study the perturbative stability of backgrounds with an AdS
G. Itsios, P. Panopoulos, K. Sfetsos, D. Zoakos   +3 more
doaj   +1 more source

Application of nonextensive statistics to particle and nuclear physics [PDF]

Physica A: Statistical Mechanics and its Applications, 2002
We present an overview of possible imprints of non-extensitivity in particle and nucler physics. Special emphasis is put on the intrinsic fluctuations present in the system under consideration as the possible source of nonextensivity. The possible connection of nonextensivity and the self organized criticality apparently being observed in some cosmic ...
G Wilk, Z Włodarczyk
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The QED nonfactorizable correction to the semileptonic charmed three-body B decays

European Physical Journal C: Particles and Fields
In this paper, the nonfactorizable photonic corrections to the effective four-fermion vertex for the $$\overline{B}$$ B ¯ $${\rightarrow }$$ → $$D^{({*})}$$ D ( ∗ ) $$+$$ + $${\ell }^{-}$$ ℓ - $$+$$ + $$\bar{\nu }_{\ell }$$ ν ¯ ℓ decays are considered at
Yueling Yang, Liting Wang, Jiazhi Li, Qin Chang, Junfeng Sun   +4 more
doaj   +1 more source

Revisiting the form factors of $$P\rightarrow V$$ P→V transition within the light-front quark models

European Physical Journal C: Particles and Fields, 2019
We investigate the self-consistency and Lorentz covariance of the covariant light-front quark model (CLF QM) via the matrix elements and form factors ($${{\mathcal {F}}}=g$$ F=g , $$a_{\pm }$$ a± and f) of $$P\rightarrow V$$ P→V transition.
Qin Chang, Xiao-Nan Li, Li-Ting Wang
doaj   +1 more source

Useful Bases for Problems in Nuclear and Particle Physics [PDF]

Journal of Computational Physics, 1997
12 pages LaTeX/revtex, plus 2 postscript ...
B. D. Keister, Wayne Polyzou
openaire   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Study on the Υ(1S)→BcM Weak Decays

Advances in High Energy Physics, 2015
Motivated by the prospects of the potential Υ(1S) particle at high-luminosity heavy-flavor experiments, we studied the Υ(1S)→BcM weak decays, where M = π, ρ, K(∗). The nonfactorizable contributions to hadronic matrix elements are taken into consideration
Junfeng Sun, Lili Chen, Na Wang, Qin Chang, Jinshu Huang, Yueling Yang   +5 more
doaj   +1 more source