Studies on the relation between heme and nucleic acid syntheses in erythroid cell. II. Nucleic acid synthesis in erythroblast of anemic rat treated with aminopterin and bromouracil [PDF]
, 1968 With the bone marrow of anemic rats, which had received the repeated injections of phenylhydrazine once a day for three to four days, the effects of aminopterin and bromouracil on the nucleic acid metabolism of erythroblasts were observed in vivo ...
Shigehisa, Morio
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Two different kinds of interaction modes of deaminase
, 2021 Yaping Liu +3 more
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Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. [PDF]
, 2007 OBJECTIVE: The normal structure and function of articular cartilage are the result of a precisely balanced interaction between anabolic and catabolic processes.
Jimenez, Sergio A. +2 more
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Reversal of terminal differentiation and control of DNA replication [PDF]
, 1993 DNA replication in mammalian cells occurs in discrete nuclear foci. Here we show that terminally differentiated myotubes can be induced to reenter S phase and show the same pattern of replication foci as cycling cells.
Cardoso, M. Cristina +2 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Ancient DNA: genomic amplification of Roman and medieval bovine bones
Italian Journal of Animal Science, 2010 Cattle remains (bones and teeth) of both roman and medieval age were collected in the archaeological site of Ferento (Viterbo, Italy) with the aim of extracting and characterising nucleic acids. Procedures to minimize contamination with modern DNA and to
A. Valentini +6 more
doaj +1 more source
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. [PDF]
, 2019 RNA Polymerase II (Pol II) and transcription factors form concentrated hubs in cells via multivalent protein-protein interactions, often mediated by proteins with intrinsically disordered regions.
Darzacq, Xavier +9 more
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Nuclear DNA content of occult sclerosing and frank papillary carcinoma of the thyroid [PDF]
, 1971 M Izuo +3 more
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